-transparent.png){kind=logo}
The present study assessed the effects of kindling on striatal DA terminals. Kindled and control rats were tested for DA transporter density using [3H]GBR-12935 binding to striatal membranes and for amphetamine and KCl-induced [3H]DA release from striatal slices. Kindling decreased the maximal number of [3H]GBR-12935 binding sites in the dorsal striatum of rats sacrificed either 2 h or 4 weeks after the last seizure but had no effect on stimulated fractional [3H]DA release. These findings suggest a minor damage to DA terminals in the dorsal striatum. At the same postseizure time points, kindling augmented the hyperlocomotion associated with novel environment. Explanation of this effect requires in vivo measures of striatal DA functioning.
I Gordon, and
M Mintz, and
E Rosenne, and
M Rehavi
January 1987,
Epilepsia,
I Gordon, and
M Mintz, and
E Rosenne, and
M Rehavi
October 1991,
Neuroscience research,
I Gordon, and
M Mintz, and
E Rosenne, and
M Rehavi
July 1994,
Neurochemical research,
I Gordon, and
M Mintz, and
E Rosenne, and
M Rehavi
January 1982,
Pharmacological research communications,
I Gordon, and
M Mintz, and
E Rosenne, and
M Rehavi
December 1979,
Experimental neurology,
I Gordon, and
M Mintz, and
E Rosenne, and
M Rehavi
October 1980,
Neuropharmacology,
I Gordon, and
M Mintz, and
E Rosenne, and
M Rehavi
July 1998,
Epilepsy research,
I Gordon, and
M Mintz, and
E Rosenne, and
M Rehavi
January 1980,
Advances in biochemical psychopharmacology,
I Gordon, and
M Mintz, and
E Rosenne, and
M Rehavi
December 1983,
Neuroscience,
I Gordon, and
M Mintz, and
E Rosenne, and
M Rehavi
January 1988,
Epilepsy research,
