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FES is a non-receptor protein tyrosine kinase expressed in hematopoietic progenitors and differentiated myeloid cells. It has recently been implicated in granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3) and erythropoietin signal transduction. To better understand the role played by FES in normal and neoplastic hematopoiesis, we used cell fractionation techniques to examine the subcellular localization of FES in myeloid cells and cell lines. FES was observed in the nuclear, granular and plasma membrane fractions of primary human neutrophils and the myeloid leukemia cell line, HL-60. The nuclear localization was confirmed by immunocytochemistry of neutrophils.
K E Yates, and
M R Lynch, and
S G Wong, and
D J Slamon, and
J C Gasson
April 2005,
DNA and cell biology,
K E Yates, and
M R Lynch, and
S G Wong, and
D J Slamon, and
J C Gasson
June 2011,
Frontiers in bioscience (Landmark edition),
K E Yates, and
M R Lynch, and
S G Wong, and
D J Slamon, and
J C Gasson
March 1998,
The Journal of biological chemistry,
K E Yates, and
M R Lynch, and
S G Wong, and
D J Slamon, and
J C Gasson
April 2012,
Chemistry & biology,
K E Yates, and
M R Lynch, and
S G Wong, and
D J Slamon, and
J C Gasson
December 2003,
The Journal of biological chemistry,
K E Yates, and
M R Lynch, and
S G Wong, and
D J Slamon, and
J C Gasson
January 2009,
International journal of oncology,
K E Yates, and
M R Lynch, and
S G Wong, and
D J Slamon, and
J C Gasson
March 2006,
The Journal of biological chemistry,
K E Yates, and
M R Lynch, and
S G Wong, and
D J Slamon, and
J C Gasson
January 2011,
Frontiers in bioscience (Landmark edition),
K E Yates, and
M R Lynch, and
S G Wong, and
D J Slamon, and
J C Gasson
February 1988,
Molecular and cellular biology,
K E Yates, and
M R Lynch, and
S G Wong, and
D J Slamon, and
J C Gasson
November 2004,
Molecular and cellular biology,
