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The study was designed to investigate the toxic effects of Rhizoma Zedoariae (RZ) and nickel sulfide, and the effect of RZ on nickel sulfide induced unscheduled DNA synthesis (UDS) of human lymphocytes using an UDS assay of human lymphocytes. The results showed that TZ did not induce UDS, it could inhibit 3H-TdR incorporation with intracellular DNA when its' dose was 1 g/ml, that nickel sulfide and ultraviolet could largely induce UDS, that might be inhibited by RZ with a dose dependent relationship. These suggested that nickel sulfide induced damage of DNA might be inhibited by RZ, RZ was not mutagenic and DNA synthesis might be inhibited when the RZ dose amounted to 1 g/ml.
Y D Li, and
X H Li, and
Y M Wang
September 1982,
Mutation research,
Y D Li, and
X H Li, and
Y M Wang
August 1969,
Radiation research,
Y D Li, and
X H Li, and
Y M Wang
July 1970,
Radiation research,
Y D Li, and
X H Li, and
Y M Wang
January 1983,
TSitologiia i genetika,
Y D Li, and
X H Li, and
Y M Wang
August 1975,
Gan,
Y D Li, and
X H Li, and
Y M Wang
September 1975,
Radiation research,
Y D Li, and
X H Li, and
Y M Wang
December 1980,
Cancer letters,
Y D Li, and
X H Li, and
Y M Wang
August 1983,
Chemico-biological interactions,
Y D Li, and
X H Li, and
Y M Wang
January 1981,
Carcinogenesis,
Y D Li, and
X H Li, and
Y M Wang
November 1979,
Tsitologiia,
