Biomaterial Database

Evaluation of the Rheuma-Lex latex agglutination test for detection of rheumatoid factor. 1993

J L Schmitz, and J D Folds

Clinical Immunology Laboratory, University of North Carolina Hospitals, Chapel Hill 27514.

The performance of the Trinity Laboratories Rheuma-Lex latex agglutination test kit for detection of Rheumatoid factor (RF) in patient sera was evaluated. The method and test results of the Rheuma-Lex test were compared to those obtained with another commercially available latex agglutination test kit (RapiTex RF Test) on 162 sera submitted for RF testing. Discrepant results were resolved by testing those sera with a third commercially available kit. The Rheuma-Lex and the RapiTex kits demonstrated sensitivities of 100 and 87%, specificities of 98 and 99%, negative predictive values of 100 and 97%, positive predictive values of 94 and 94% and efficiencies of 99 and 97% respectively. The Rheuma-Lex test kit was judged to be a sensitive, reliable and simple assay for RF detection in serum.

UI	MeSH Term	Description	Entries
D007841	Latex Fixation Tests	Passive agglutination tests in which antigen is adsorbed onto latex particles which then clump in the presence of antibody specific for the adsorbed antigen. (From Stedman, 26th ed)	Latex Agglutination Tests,Agglutination Test, Latex,Agglutination Tests, Latex,Fixation Test, Latex,Fixation Tests, Latex,Latex Agglutination Test,Latex Fixation Test,Test, Latex Agglutination,Test, Latex Fixation,Tests, Latex Agglutination,Tests, Latex Fixation
D011446	Prospective Studies	Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.	Prospective Study,Studies, Prospective,Study, Prospective
D011933	Reagent Kits, Diagnostic	Commercially prepared reagent sets, with accessory devices, containing all of the major components and literature necessary to perform one or more designated diagnostic tests or procedures. They may be for laboratory or personal use.	Diagnostic Reagent Kits,Diagnostic Reagents and Test Kits,Diagnostic Test Kits,In Vitro Diagnostic Device,In Vitro Diagnostic Devices,In Vitro Diagnostic Medical Device,In Vitro Diagnostic Medical Devices,Kits, Diagnostic Reagent,Diagnostic Reagent Kit,Diagnostic Test Kit,Kit, Diagnostic Reagent,Kit, Diagnostic Test,Kits, Diagnostic Test,Reagent Kit, Diagnostic,Test Kit, Diagnostic,Test Kits, Diagnostic
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012217	Rheumatoid Factor	Autoantibodies found in adult RHEUMATOID ARTHRITIS patients that are directed against GAMMA-CHAIN IMMUNOGLOBULINS.	Factor, Rheumatoid