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Intravenously infused bovine trypsin, 75 mg kg-1 during 3 h, induced shock in rats which proved lethal. After 5 h, all the rats had died. In another group of rats receiving trypsin, the pancreatic secretory trypsin inhibitor, 75 mg kg-1, was infused during 5 h. These rats all survived. After about 1 h, alpha 1-macroglobulin was found to be saturated in both groups, while kininogen cleavage, coinciding with a decline in arterial blood pressure, only occurred in the untreated group. Trypsin complex formation with alpha 1-inhibitor 3 and alpha 1-proteinase inhibitor was more pronounced in untreated rats. It is concluded that the pancreatic secretory trypsin inhibitor may function as an effective trypsin inhibitor in plasma.
P Jönsson, and
I Ljungcrantz, and
K Ohlsson
February 1995,
Nihon rinsho. Japanese journal of clinical medicine,
P Jönsson, and
I Ljungcrantz, and
K Ohlsson
January 1976,
Methods in enzymology,
P Jönsson, and
I Ljungcrantz, and
K Ohlsson
November 2004,
Nihon rinsho. Japanese journal of clinical medicine,
P Jönsson, and
I Ljungcrantz, and
K Ohlsson
August 1999,
Nihon rinsho. Japanese journal of clinical medicine,
P Jönsson, and
I Ljungcrantz, and
K Ohlsson
June 2010,
World journal of gastrointestinal pathophysiology,
P Jönsson, and
I Ljungcrantz, and
K Ohlsson
January 1988,
Advances in experimental medicine and biology,
P Jönsson, and
I Ljungcrantz, and
K Ohlsson
September 1984,
Clinica chimica acta; international journal of clinical chemistry,
P Jönsson, and
I Ljungcrantz, and
K Ohlsson
January 1992,
Digestion,
P Jönsson, and
I Ljungcrantz, and
K Ohlsson
October 1989,
Hinyokika kiyo. Acta urologica Japonica,
P Jönsson, and
I Ljungcrantz, and
K Ohlsson
September 1985,
Journal of biochemistry,
