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The aim of this study is to compare the effects of low dose cyclosporin A (CsA) and intravenous cyclophosphamide pulses (IV-CTX) in the treatment of lupus nephritis (LN). Thirty patients were included in the study with 15 in each group. The improvement of ESR and proteinuria and the increase of serum albumin were observed in the CsA group, but not in the IV-CTX group at the early stage of the therapy, though the overall effects were similar. The conclusion is that the use of low dose CsA could quench the activity of LN at the early stage of the therapy, reduce the doses of steroid and CTX and minimire their side effects. IV-CTX was added to 8 cases of LN before CsA treatment had been tapered of or withdrawn. The results indicated that this regimen could effectively prevent the relapse of LN after the withdrawal of CsA therapy. It is an effective and valuable therapy.
P D Yin, and
X Y Yang
May 2018,
Modern rheumatology,
P D Yin, and
X Y Yang
August 1998,
QJM : monthly journal of the Association of Physicians,
P D Yin, and
X Y Yang
January 1995,
Contributions to nephrology,
P D Yin, and
X Y Yang
February 1998,
British journal of rheumatology,
P D Yin, and
X Y Yang
January 2007,
Modern rheumatology,
P D Yin, and
X Y Yang
April 1994,
Arthritis and rheumatism,
P D Yin, and
X Y Yang
October 2016,
BMC nephrology,
P D Yin, and
X Y Yang
November 1991,
Lupus,
P D Yin, and
X Y Yang
January 2001,
Lupus,
P D Yin, and
X Y Yang
August 2002,
Arthritis and rheumatism,
