Biomaterial Database

[Observation of cochlear microcirculation in experimental endolymphatic hydrops]. 1994

C Zhou, and S Zhang, and B Hu

PLA General Hospital, Beijing.

30 guinea pigs were made as a model of endolymphatic hydrops by obliteration of endolymphatic sac and duct. Cochlear microcirculation of the lateral wall in the third turn was observed and recorded. The diameters and velocities of the vessels were analysed in IBAS image system. The stria vascular vessels and spiral ligament vessels were analysed respectively. The data showed: 1. 1, 2 and 3 months after operation, the diameter of SLV averaely decreased 0.80 microns, 0.87 microns, 1.21 microns (P < 0.05) respectively and velocity decreased 100.8 microns/s, 141.0 microns/s, 136.0 microns/s (P < 0.05) respectively. 2. The diameter of SVV dilated 3 months after operation. With the elapse of time, SVV had a dilation tendency. These indicated that hydrops effect different changes in SLV and SVV. The overpressure of endolymphatic fluid may be the possible cause of changes in SVV and SLV.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008833	Microcirculation	The circulation of the BLOOD through the MICROVASCULAR NETWORK.	Microvascular Blood Flow,Microvascular Circulation,Blood Flow, Microvascular,Circulation, Microvascular,Flow, Microvascular Blood,Microvascular Blood Flows,Microvascular Circulations
D003051	Cochlea	The part of the inner ear (LABYRINTH) that is concerned with hearing. It forms the anterior part of the labyrinth, as a snail-like structure that is situated almost horizontally anterior to the VESTIBULAR LABYRINTH.	Cochleas
D003053	Cochlear Duct	A spiral tube that is firmly suspended in the bony shell-shaped part of the cochlea. This ENDOLYMPH-filled cochlear duct begins at the vestibule and makes 2.5 turns around a core of spongy bone (the modiolus) thus dividing the PERILYMPH-filled spiral canal into two channels, the SCALA VESTIBULI and the SCALA TYMPANI.	Ductus Cochlearis,Scala Media,Cochlear Ducts,Cochlearis, Ductus,Duct, Cochlear,Ducts, Cochlear,Media, Scala,Medias, Scala,Scala Medias
D006168	Guinea Pigs	A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.	Cavia,Cavia porcellus,Guinea Pig,Pig, Guinea,Pigs, Guinea
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013316	Stria Vascularis	A layer of stratified EPITHELIUM forming the endolymphatic border of the cochlear duct at the lateral wall of the cochlea. Stria vascularis contains primarily three cell types (marginal, intermediate, and basal), and capillaries. The marginal cells directly facing the ENDOLYMPH are important in producing ion gradients and endochoclear potential.	Vascularis, Stria
D018159	Endolymphatic Hydrops	An accumulation of ENDOLYMPH in the inner ear (LABYRINTH) leading to buildup of pressure and distortion of intralabyrinthine structures, such as COCHLEA and SEMICIRCULAR CANALS. It is characterized by SENSORINEURAL HEARING LOSS; TINNITUS; and sometimes VERTIGO.	Hydrops, Endolymphatic

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