Biomaterial Database

[Treatment of bladder cancer by Nd:YAG laser local irradiation and whole-bladder photodynamic therapy with hematoporphyrin derivative]. 1994

C L Li, and B Z Xu, and X Y Shong

Department of Urological Oncology and Laser Medicine, Chinese Academy of Medical Sciences, Peking Union of Medical College, Beijing.

Twenty cases with 51 tumor foci of urinary bladder were treated by Nd:YAG laser local irradiation plus whole-bladder photodynamic therapy (PDT) with hematoporphyrin derivative (HPD). All cases were confirmed by histopathological diagnosis. Of the 20 patients, 19 were cured after one treatment (95%) and the other patient cured after 2 treatments within 40 days. On follow-up for 3-23 months, tumor recurrence occurred in 2 cases (10%) about 3-6 months after treatment. The results suggest that the PDT effect in destroying bladder tumors might be enhanced by Nd:YAG laser while the lesions escaped Nd:YAG laser irradiation could be handled by whole-bladder PDT.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009364	Neoplasm Recurrence, Local	The local recurrence of a neoplasm following treatment. It arises from microscopic cells of the original neoplasm that have escaped therapeutic intervention and later become clinically visible at the original site.	Local Neoplasm Recurrence,Local Neoplasm Recurrences,Locoregional Neoplasm Recurrence,Neoplasm Recurrence, Locoregional,Neoplasm Recurrences, Local,Recurrence, Local Neoplasm,Recurrence, Locoregional Neoplasm,Recurrences, Local Neoplasm,Locoregional Neoplasm Recurrences,Neoplasm Recurrences, Locoregional,Recurrences, Locoregional Neoplasm
D001749	Urinary Bladder Neoplasms	Tumors or cancer of the URINARY BLADDER.	Bladder Cancer,Bladder Neoplasms,Cancer of Bladder,Bladder Tumors,Cancer of the Bladder,Malignant Tumor of Urinary Bladder,Neoplasms, Bladder,Urinary Bladder Cancer,Bladder Cancers,Bladder Neoplasm,Bladder Tumor,Cancer, Bladder,Cancer, Urinary Bladder,Neoplasm, Bladder,Neoplasm, Urinary Bladder,Tumor, Bladder,Tumors, Bladder,Urinary Bladder Neoplasm
D002295	Carcinoma, Transitional Cell	A malignant neoplasm derived from TRANSITIONAL EPITHELIAL CELLS, occurring chiefly in the URINARY BLADDER; URETERS; or RENAL PELVIS.	Carcinomas, Transitional Cell,Cell Carcinoma, Transitional,Cell Carcinomas, Transitional,Transitional Cell Carcinoma,Transitional Cell Carcinomas
D003131	Combined Modality Therapy	The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.	Multimodal Treatment,Therapy, Combined Modality,Combined Modality Therapies,Modality Therapies, Combined,Modality Therapy, Combined,Multimodal Treatments,Therapies, Combined Modality,Treatment, Multimodal,Treatments, Multimodal
D005260	Female		Females
D006414	Hematoporphyrin Photoradiation	Photochemotherapy using visible light, usually red, topically or delivered locally by fiberoptic probe to tissues sensitized with hematoporphyrins.	Photochemotherapy, Hematoporphyrin,Photoradiation, Hematoporphyrin,Hematoporphyrin Photochemotherapy
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults