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Detection of early atherosclerosis by analysis of ultrasonic Doppler signals produced by mural flow disturbances. 1994

T M Robinson, and J W Lee, and V C Roberts
Department of Medical Engineering & Physics, King's College School of Medicine & Dentistry, London, UK.

The paper describes an in vitro study using a multi-gate Doppler ultrasound system to investigate flow disturbances in a blood analogue caused by small stenoses (2-25% cross-sectional area reduction), using steady flow (100-600 ml min-1) in a 6 mm diameter rigid artery model. The results indicate that stenoses greater than 5% were detectable.

UI MeSH Term Description Entries
D008955 Models, Cardiovascular Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment. Cardiovascular Model,Cardiovascular Models,Model, Cardiovascular
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001158 Arteries The vessels carrying blood away from the heart. Artery
D001161 Arteriosclerosis Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries. Arterioscleroses
D018056 Hemorheology The deformation and flow behavior of BLOOD and its elements i.e., PLASMA; ERYTHROCYTES; WHITE BLOOD CELLS; and BLOOD PLATELETS. Hemorrheology
D018617 Ultrasonography, Doppler, Pulsed Ultrasonography applying the Doppler effect, with velocity detection combined with range discrimination. Short bursts of ultrasound are transmitted at regular intervals and the echoes are demodulated as they return. Doppler Ultrasonography, Pulsed,Ultrasonography, Pulsed Doppler,Doppler Pulsed Ultrasonography,Pulsed Doppler Ultrasonography,Pulsed Ultrasonography, Doppler,Ultrasonography, Doppler Pulsed

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