Biomaterial Database

Schweigger-Seidel sheath or ellipsoid in the spleen of guinea hen. 1994

I Oláh, and A Kupper, and P Dúcz

Second Department of Anatomy, Semmelweis University Medical School, Budapest, Hungary.

Splenic Schweigger-Seidel sheath or ellipsoid was studied by anti-vimentin monoclonal antibodies, clones 3B4 and V9. The 3B4 mAb recognizes a cell type with cytoplasmic granules and long processes which make a network around the endothelial cells of the penicilliform capillaries. The V9 mAb identifies the reticular cells of the spleen which form the supporting system of the Schweigger-Seidel sheath. The sheath covers the entire length of the penicilliform capillary from the central artery, including the branching area. The appearance of the Schweigger-Seidel sheath in a section depends on the section plane; namely, at the branching area its shape is highly irregular, while close to the red pulp it looks like a sleeve. Therefore, the English term "ellipsoid" does not cover the morphological appearance of this unique splenic structure; the Schweigger-Seidel sheath is a correct term.

UI	MeSH Term	Description	Entries
D011200	Poultry	Domesticated birds raised for food. It typically includes CHICKENS; TURKEYS, DUCKS; GEESE; and others.	Fowls, Domestic,Domestic Fowl,Domestic Fowls,Fowl, Domestic,Poultries
D005260	Female		Females
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D000911	Antibodies, Monoclonal	Antibodies produced by a single clone of cells.	Monoclonal Antibodies,Monoclonal Antibody,Antibody, Monoclonal
D013154	Spleen	An encapsulated lymphatic organ through which venous blood filters.
D014746	Vimentin	An intermediate filament protein found in most differentiating cells, in cells grown in tissue culture, and in certain fully differentiated cells. Its insolubility suggests that it serves a structural function in the cytoplasm. MW 52,000.