Biomaterial Database

Fine-wire localization for nonpalpable mammographic abnormalities. 1995

L M Fedoruk, and M A Bojm, and S P Bugis

Department of Surgery, Royal Columbian Hospital, New Westminster, BC.

OBJECTIVE To determine the predictive value of fine-wire localization (FWL) biopsy. METHODS A chart review. METHODS The Royal Columbian Hospital, New Westminster, BC. METHODS Two hundred and thirty-five women who underwent 239 biopsies for abnormal mammographic findings between Jan. 1, 1991, and Dec. 31, 1992. The average age was 58 years (range from 33 to 83 years). METHODS FWL biopsy. METHODS Positive findings of cancer on FWL biopsy. RESULTS Mammographic findings were as follows: a mass only in 98 cases (41.0%), microcalcification in 90 (37.7%), a spiculated mass in 20 (7.5%), an ill-defined density in 18 (8.4%) and a mass with microcalcification in 13 (5.4%). Malignant lesions were found in 97 (40.6%) of 239 biopsies. These included 55 infiltrating ductal carcinomas, 31 in-situ carcinomas, 7 infiltrating lobular carcinomas and 4 miscellaneous carcinomas. Spiculated masses were associated with malignancy in 18 (90%) of the 20 biopsies. Also, 41 (42%) of the 98 masses and 30 (33%) of the 90 microcalcifications were malignant. Only 4 (31%) of the 13 masses with associated microcalcification and 4 (22%) of the 18 ill-defined densities were malignant. CONCLUSIONS The 40.6% rate of positive findings supports the use of FWL biopsy as a valuable tool in the diagnosis of nonpalpable breast cancers.

UI	MeSH Term	Description	Entries
D008327	Mammography	Radiographic examination of the breast.	3D-Mammography,Digital Breast Tomosynthesis,Digital Mammography,X-ray Breast Tomosynthesis,3D Mammography,3D-Mammographies,Breast Tomosyntheses, Digital,Breast Tomosyntheses, X-ray,Breast Tomosynthesis, Digital,Breast Tomosynthesis, X-ray,Digital Breast Tomosyntheses,Digital Mammographies,Mammographies,Mammographies, Digital,Mammography, Digital,X ray Breast Tomosynthesis,X-ray Breast Tomosyntheses
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D011230	Precancerous Conditions	Pathological conditions that tend eventually to become malignant.	Preneoplastic Conditions,Condition, Preneoplastic,Conditions, Preneoplastic,Preneoplastic Condition,Condition, Precancerous,Conditions, Precancerous,Precancerous Condition
D011237	Predictive Value of Tests	In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.	Negative Predictive Value,Positive Predictive Value,Predictive Value Of Test,Predictive Values Of Tests,Negative Predictive Values,Positive Predictive Values,Predictive Value, Negative,Predictive Value, Positive
D001941	Breast Diseases	Pathological processes of the BREAST.	Endocrine Breast Diseases,Breast Disease,Breast Disease, Endocrine,Breast Diseases, Endocrine,Disease, Breast,Disease, Endocrine Breast,Diseases, Breast,Diseases, Endocrine Breast,Endocrine Breast Disease
D001943	Breast Neoplasms	Tumors or cancer of the human BREAST.	Breast Cancer,Breast Tumors,Cancer of Breast,Breast Carcinoma,Cancer of the Breast,Human Mammary Carcinoma,Malignant Neoplasm of Breast,Malignant Tumor of Breast,Mammary Cancer,Mammary Carcinoma, Human,Mammary Neoplasm, Human,Mammary Neoplasms, Human,Neoplasms, Breast,Tumors, Breast,Breast Carcinomas,Breast Malignant Neoplasm,Breast Malignant Neoplasms,Breast Malignant Tumor,Breast Malignant Tumors,Breast Neoplasm,Breast Tumor,Cancer, Breast,Cancer, Mammary,Cancers, Mammary,Carcinoma, Breast,Carcinoma, Human Mammary,Carcinomas, Breast,Carcinomas, Human Mammary,Human Mammary Carcinomas,Human Mammary Neoplasm,Human Mammary Neoplasms,Mammary Cancers,Mammary Carcinomas, Human,Neoplasm, Breast,Neoplasm, Human Mammary,Neoplasms, Human Mammary,Tumor, Breast
D003937	Diagnosis, Differential	Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures.	Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults