-transparent.png){kind=logo}
Antithyroid peroxidase antibodies (TPOAb) were determined by competitive radioassay in serum samples obtained from a representative population of 85-year-olds (601 women and 285 men). The prevalence of increased TPOAb concentration was significantly higher in the women. In individuals without previously known thyroid dysfunction, 16% of the women and 9% of the men had TPOAb concentration > 100 kilo-units/L, the upper decision limit. We found a direct relationship between TPOAb and thyrotropin (TSH) concentrations and an inverse relationship between TPOAb and free thyroxine (T4) concentrations, but no relationship between TPOAb and defined disorders or treatment with pharmaceutical drugs. Exclusion of individuals with increased TPOAb concentration and conditions influencing TSH and free T4 concentrations resulted in a decrease of the upper reference limit for TSH concentration and an increase of the lower limit for free T4 concentration, indicating that high TPOAb concentration should be taken into account when evaluating normal reference intervals for thyroid-function tests in the elderly.
G Sundbeck, and
S Edén, and
R Jagenburg, and
P A Lundberg, and
G Lindstedt
November 1990,
Age and ageing,
G Sundbeck, and
S Edén, and
R Jagenburg, and
P A Lundberg, and
G Lindstedt
December 1999,
Nihon rinsho. Japanese journal of clinical medicine,
G Sundbeck, and
S Edén, and
R Jagenburg, and
P A Lundberg, and
G Lindstedt
February 2017,
Journal of obstetrics and gynaecology of India,
G Sundbeck, and
S Edén, and
R Jagenburg, and
P A Lundberg, and
G Lindstedt
December 2013,
Iranian journal of reproductive medicine,
G Sundbeck, and
S Edén, and
R Jagenburg, and
P A Lundberg, and
G Lindstedt
January 1994,
Archives of gerontology and geriatrics,
G Sundbeck, and
S Edén, and
R Jagenburg, and
P A Lundberg, and
G Lindstedt
September 1994,
Age and ageing,
G Sundbeck, and
S Edén, and
R Jagenburg, and
P A Lundberg, and
G Lindstedt
January 1991,
Scandinavian journal of caring sciences,
G Sundbeck, and
S Edén, and
R Jagenburg, and
P A Lundberg, and
G Lindstedt
January 1992,
Archives of gerontology and geriatrics,
G Sundbeck, and
S Edén, and
R Jagenburg, and
P A Lundberg, and
G Lindstedt
January 2009,
Polskie Archiwum Medycyny Wewnetrznej,
G Sundbeck, and
S Edén, and
R Jagenburg, and
P A Lundberg, and
G Lindstedt
December 1991,
Community dentistry and oral epidemiology,
