Authors report their personal experience on Roux-en-Y reconstruction, after partial gastric resection. They have considered 39 patients: 24 of them had been operated for a peptic ulcer of the lesser gastric curve and 15 for a pyloric cancer for which a partial gastric resection had been adopted for various reasons (age, stage or else). The follow-up lasted on an average of 42 months (4 to 68). Controls concerned secretory activity and motility. A prolonged stasis of solids, in the gastric stump or in the isolated loop, has been observed in two of the long controlled patients, together with superficial ulcers of the digiunal mucosa. Alcaline reflux was absent or very small; inflammatory changes of the gastric mucosa were hardly evident. In conclusion the authors regard the partial gastric resection, followed by the reconstruction with a digiunal isolated loop, as a valid surgical technique, for peptic ulcers of lesser gastric curve and for gastric cancers for which total gastrectomy seems not indicate.