-transparent.png){kind=logo}
We have isolated a cDNA (named P450 A) which is a variant of CYP2E1 presenting some differences in the 3' non coding region. Two substitutions and only one polyadenylation signal were detected on P450 A compared to CYP2E1 where there are two. With the aim of studying the frequency of utilization of these polyadenylation signals, probe A and probe J specific for P450 A and CYP2E1, respectively, were hybridized on human hepatic and extra-hepatic cDNA samples. Results indicated that in all tissues tested only P450 A using the first polyadenylation signal was detected. The CYP2E1 cDNA isolated by Song et al could be representative of a transcript either rarely represented among the Caucasian population, or expressed in a particular individual or ethnic population, or rapidly degraded.
E M Seree, and
F Botto, and
P Pisano, and
E Lechevalier, and
A Desobry, and
Y Barra
January 2009,
In silico biology,
E M Seree, and
F Botto, and
P Pisano, and
E Lechevalier, and
A Desobry, and
Y Barra
March 2000,
FEBS letters,
E M Seree, and
F Botto, and
P Pisano, and
E Lechevalier, and
A Desobry, and
Y Barra
October 1994,
Thrombosis research,
E M Seree, and
F Botto, and
P Pisano, and
E Lechevalier, and
A Desobry, and
Y Barra
January 2005,
Cytogenetic and genome research,
E M Seree, and
F Botto, and
P Pisano, and
E Lechevalier, and
A Desobry, and
Y Barra
April 1999,
Gene,
E M Seree, and
F Botto, and
P Pisano, and
E Lechevalier, and
A Desobry, and
Y Barra
July 1994,
Gene,
E M Seree, and
F Botto, and
P Pisano, and
E Lechevalier, and
A Desobry, and
Y Barra
March 1990,
The Journal of biological chemistry,
E M Seree, and
F Botto, and
P Pisano, and
E Lechevalier, and
A Desobry, and
Y Barra
January 1977,
Advances in experimental medicine and biology,
E M Seree, and
F Botto, and
P Pisano, and
E Lechevalier, and
A Desobry, and
Y Barra
June 1980,
Biochemical Society transactions,
E M Seree, and
F Botto, and
P Pisano, and
E Lechevalier, and
A Desobry, and
Y Barra
September 1959,
Lancet (London, England),
