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Eight clinical isolates and two reference strains of Helicobacter pylori were studied with regard to their interactions with HeLa cells. All the isolates adhered poorly to HeLa cells and the number of invasive bacteria was very low. No correlation was found between the adherence and invasiveness of the isolates on one hand, and the corresponding patients having ulcer or non-ulcer disease, or the ability of the strains to produce cytotoxin and to induce an oxidative burst of human polymorphonuclear leukocytes without opsonins, on the other. These results indicate that invasion of epithelial cells would play no important role in the pathogenesis of infections caused by H. pylori.
H Rautelin, and
E Kihlström, and
M Jurstrand, and
D Danielsson
January 2016,
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H Rautelin, and
E Kihlström, and
M Jurstrand, and
D Danielsson
December 1998,
Zentralblatt fur Bakteriologie : international journal of medical microbiology,
H Rautelin, and
E Kihlström, and
M Jurstrand, and
D Danielsson
January 2006,
Methods in enzymology,
H Rautelin, and
E Kihlström, and
M Jurstrand, and
D Danielsson
January 2019,
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H Rautelin, and
E Kihlström, and
M Jurstrand, and
D Danielsson
September 1995,
Gastroenterology,
H Rautelin, and
E Kihlström, and
M Jurstrand, and
D Danielsson
July 2010,
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas,
H Rautelin, and
E Kihlström, and
M Jurstrand, and
D Danielsson
December 1990,
Microbial pathogenesis,
H Rautelin, and
E Kihlström, and
M Jurstrand, and
D Danielsson
September 1998,
Digestive diseases and sciences,
H Rautelin, and
E Kihlström, and
M Jurstrand, and
D Danielsson
August 1999,
Digestive diseases and sciences,
H Rautelin, and
E Kihlström, and
M Jurstrand, and
D Danielsson
January 1993,
Molecular microbiology,
