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HPLC of crude Dermostatin indicated presence of three pairs of components. Hence, attempts were made to purify Dermostatin. Purification of crude Dermostatin has been carried out using column chromatography and counter current distribution methods. Each of these fractions were tested for activity. The major fraction which showed greater activity was taken for the preparation of Dermostatin nona-acetate. Structural characterisation of Dermostatin nona-acetate has been carried out using UV-visible spectroscopy in different solvents to obtain the characteristic spectrum of a carbonyl conjugated hexaene at room temperature. Structural and configurational studies of Dermostatin nona-acetate using 500 MHz 1H NMR and 125 MHz 13C NMR has been used in the assignment of various functional groups in Dermostatin A and B as well as to provide corroboration to the earlier structural elucidation.
M B Swamy, and
M K Sastry, and
R K Nanda
March 1995,
Analytical chemistry,
M B Swamy, and
M K Sastry, and
R K Nanda
May 1985,
Biochemistry,
M B Swamy, and
M K Sastry, and
R K Nanda
May 1988,
Carbohydrate research,
M B Swamy, and
M K Sastry, and
R K Nanda
November 1976,
FEBS letters,
M B Swamy, and
M K Sastry, and
R K Nanda
February 1998,
Carbohydrate research,
M B Swamy, and
M K Sastry, and
R K Nanda
December 2005,
Magnetic resonance in chemistry : MRC,
M B Swamy, and
M K Sastry, and
R K Nanda
February 2009,
Molecular bioSystems,
M B Swamy, and
M K Sastry, and
R K Nanda
April 1989,
Analytical biochemistry,
M B Swamy, and
M K Sastry, and
R K Nanda
October 1983,
Journal of biomolecular structure & dynamics,
M B Swamy, and
M K Sastry, and
R K Nanda
January 1984,
Biochemistry,
