-transparent.png){kind=logo}
There are several reports of an increased occurrence of nonparathyroid cancer in patients with primary hyperparathyroidism. Whether there is a cause and effect relationship has not been established. Especially, the coexistence of the parathyroid and thyroid tumors appears significantly high. Recently PRAD 1 was determined the one of the oncogenes of parathyroid adenoma. Interest in PRAD 1's role with respect to oncogenesis has been intensified by its incrimination in other, nonparathyroid, human tumors. If properly conducted surveillance programs do indicate a higher likelihood of cancer in patients with primary hyperparathyroidism, the current philosophy that the patient with mild and asymptomatic hyperparathyroidism does not need the surgery must be reevaluated.
K Nutahara, and
E Higashihara
January 1997,
Vestnik otorinolaringologii,
K Nutahara, and
E Higashihara
February 1967,
Klinicheskaia khirurgiia,
K Nutahara, and
E Higashihara
September 1971,
Akusherstvo i ginekologiia,
K Nutahara, and
E Higashihara
May 1965,
Zentralblatt fur Gynakologie,
K Nutahara, and
E Higashihara
September 2017,
European journal of internal medicine,
K Nutahara, and
E Higashihara
January 1993,
Dermatology (Basel, Switzerland),
K Nutahara, and
E Higashihara
January 1956,
Voprosy onkologii,
K Nutahara, and
E Higashihara
May 1970,
Medizinische Klinik,
K Nutahara, and
E Higashihara
August 1999,
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology,
K Nutahara, and
E Higashihara
January 2000,
Voprosy onkologii,
