-transparent.png){kind=logo}
Golden Syrian hamster pups were administered a single subcutaneous dose of 203Hg-labeled methyl mercury (MeHg), 0.4 nmol/g body weight, seven days after birth, and were sacrificed 2, 7, 14, 21 or 28 days later. The excretion of 203Hg followed a biphasic elimination pattern with an average half-time of 8.7 days for the rapid component. The slow component had a much longer half-time and probably reflects binding of 203Hg to growing hair. The concentration of 203Hg in the liver, kidneys and brain two days after administration was 0.44, 0.38 and 0.19 nmol/g, respectively. The retention of 203Hg was higher in the kidney than in the liver and the brain. The content of inorganic 203Hg in the liver and kidneys increased the first weeks after administration, demonstrating that hamsters are able to demethylate MeHg before two weeks of age.
L Dock, and
R L Rissanen, and
M Vahter
October 1969,
Archives of environmental health,
L Dock, and
R L Rissanen, and
M Vahter
December 1970,
Archives of environmental health,
L Dock, and
R L Rissanen, and
M Vahter
May 1971,
Archives of environmental health,
L Dock, and
R L Rissanen, and
M Vahter
August 1995,
Pharmacology & toxicology,
L Dock, and
R L Rissanen, and
M Vahter
October 1976,
Health physics,
L Dock, and
R L Rissanen, and
M Vahter
January 1969,
Nordisk hygienisk tidskrift,
L Dock, and
R L Rissanen, and
M Vahter
May 1974,
Poultry science,
L Dock, and
R L Rissanen, and
M Vahter
June 1978,
Japanese journal of pharmacology,
L Dock, and
R L Rissanen, and
M Vahter
January 1982,
Radioisotopes,
L Dock, and
R L Rissanen, and
M Vahter
December 1973,
The Journal of pharmacology and experimental therapeutics,
