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The molecular mechanisms of the inhibitory action of fructose- 2,6-bisphosphate (F-2,6-P2) on fructose-1,6-biphosphatase (FB-Pase-1), the key enzyme of gluconeogenesis, and the those of the activating action of F-2,6-P2 on phosphofructo-1-kinase (PFK-1), the key enzyme of glycolysis, NMR spectroscopy first provided direct evidence for the fact that F-2,6-P2 was involved in the regulation of the sedoheptulose cycle of a nonoxidative stage of the pentosephosphate pathway. Procedures were developed in measuring the levels of F-2,6-P2 in the cell of experimental animal tissues and human blood lymphocytes. Naturally different emergencies substantially affected the F-2,6-P2 system by triggering these or those mechanisms controlling the activity of enzymes of this system. Vanadium-containing compounds were demonstrated to have a positive action on carbohydrate metabolism in diabetic (streptozotocin-induced) rat hepatocytes.
B F Korovkin, and
N F Beliaeva, and
L N Viktorova, and
M A Golubev, and
V K Gorodetskiĭ, and
M S Markova, and
A V Saiapin, and
N S Stvolinskaia
January 1987,
Advances in enzymology and related areas of molecular biology,
B F Korovkin, and
N F Beliaeva, and
L N Viktorova, and
M A Golubev, and
V K Gorodetskiĭ, and
M S Markova, and
A V Saiapin, and
N S Stvolinskaia
June 1983,
Biochemical Society transactions,
B F Korovkin, and
N F Beliaeva, and
L N Viktorova, and
M A Golubev, and
V K Gorodetskiĭ, and
M S Markova, and
A V Saiapin, and
N S Stvolinskaia
May 1987,
The Biochemical journal,
B F Korovkin, and
N F Beliaeva, and
L N Viktorova, and
M A Golubev, and
V K Gorodetskiĭ, and
M S Markova, and
A V Saiapin, and
N S Stvolinskaia
December 1981,
Biochemical and biophysical research communications,
B F Korovkin, and
N F Beliaeva, and
L N Viktorova, and
M A Golubev, and
V K Gorodetskiĭ, and
M S Markova, and
A V Saiapin, and
N S Stvolinskaia
January 2004,
The Pharos of Alpha Omega Alpha-Honor Medical Society. Alpha Omega Alpha,
B F Korovkin, and
N F Beliaeva, and
L N Viktorova, and
M A Golubev, and
V K Gorodetskiĭ, and
M S Markova, and
A V Saiapin, and
N S Stvolinskaia
June 1986,
Archives internationales de physiologie et de biochimie,
B F Korovkin, and
N F Beliaeva, and
L N Viktorova, and
M A Golubev, and
V K Gorodetskiĭ, and
M S Markova, and
A V Saiapin, and
N S Stvolinskaia
June 1988,
Journal of biochemistry,
B F Korovkin, and
N F Beliaeva, and
L N Viktorova, and
M A Golubev, and
V K Gorodetskiĭ, and
M S Markova, and
A V Saiapin, and
N S Stvolinskaia
December 1988,
Plant physiology,
B F Korovkin, and
N F Beliaeva, and
L N Viktorova, and
M A Golubev, and
V K Gorodetskiĭ, and
M S Markova, and
A V Saiapin, and
N S Stvolinskaia
June 1987,
Plant physiology,
B F Korovkin, and
N F Beliaeva, and
L N Viktorova, and
M A Golubev, and
V K Gorodetskiĭ, and
M S Markova, and
A V Saiapin, and
N S Stvolinskaia
April 1981,
The Journal of biological chemistry,
