The Brno School of Pharmaceutical Chemistry began to form when RNDr. PhMr. Bohuslav Melichar came to the Institute of Pharmaceutical Chemistry of Masaryk University of Brno in 1945. Together with other lecturers, particularly RNDr. PhMr. Ales Sekera, they created a new conception of pharmaceutical chemistry based on the classification of chemical drugs according to their pharmacological effect, the principal emphasis being laid on the investigation of dependences between the chemical structures and their effects. The discipline was divided into theoretical-systematical, control-analytical and synthetic parts. The development of the conception continued after 1960 at the Faculty of Pharmacy, Comenius University, Bratislava, and after 1969 at the Faculty of Pharmacy, Charles University, Hradec Králové. A large number of workers, lecturers who educated numerous experts for research and practice, participated in the School within this period.