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We describe two patients with Wegener's granulomatosis involving the pituitary. The diagnosis of Wegener's granulomatosis was inferred from the histological appearance of biopsy tissue and the presence of anti-neutrophil cytoplasmic antibodies with cytoplasmic distribution in the first case, in which disease remained confined to the pituitary, causing anterior and posterior pituitary dysfunction. In the second case the diagnosis was made by the progressive involvement of other organ systems, compatible histology and the presence of anti-neutrophil cytoplasmic antibodies with cytoplasmic distribution. In neither patient did posterior pituitary dysfunction respond to immunosuppressive therapy, despite remission of other features of systemic vasculitis. Panhypopituitarism in association with isolated pituitary Wegener's granulomatosis has not previously been described.
G A Roberts, and
E Eren, and
H Sinclair, and
M Pelling, and
A Burns, and
R Bradford, and
R Maurice-Williams, and
C M Black, and
N Finer, and
P M Bouloux
December 2004,
Presse medicale (Paris, France : 1983),
G A Roberts, and
E Eren, and
H Sinclair, and
M Pelling, and
A Burns, and
R Bradford, and
R Maurice-Williams, and
C M Black, and
N Finer, and
P M Bouloux
March 1999,
AJNR. American journal of neuroradiology,
G A Roberts, and
E Eren, and
H Sinclair, and
M Pelling, and
A Burns, and
R Bradford, and
R Maurice-Williams, and
C M Black, and
N Finer, and
P M Bouloux
July 2005,
Urology,
G A Roberts, and
E Eren, and
H Sinclair, and
M Pelling, and
A Burns, and
R Bradford, and
R Maurice-Williams, and
C M Black, and
N Finer, and
P M Bouloux
July 1969,
British dental journal,
G A Roberts, and
E Eren, and
H Sinclair, and
M Pelling, and
A Burns, and
R Bradford, and
R Maurice-Williams, and
C M Black, and
N Finer, and
P M Bouloux
September 1999,
Cutis,
G A Roberts, and
E Eren, and
H Sinclair, and
M Pelling, and
A Burns, and
R Bradford, and
R Maurice-Williams, and
C M Black, and
N Finer, and
P M Bouloux
November 1958,
The Journal of laryngology and otology,
G A Roberts, and
E Eren, and
H Sinclair, and
M Pelling, and
A Burns, and
R Bradford, and
R Maurice-Williams, and
C M Black, and
N Finer, and
P M Bouloux
September 1996,
British journal of urology,
G A Roberts, and
E Eren, and
H Sinclair, and
M Pelling, and
A Burns, and
R Bradford, and
R Maurice-Williams, and
C M Black, and
N Finer, and
P M Bouloux
March 1976,
Journal of clinical pathology,
G A Roberts, and
E Eren, and
H Sinclair, and
M Pelling, and
A Burns, and
R Bradford, and
R Maurice-Williams, and
C M Black, and
N Finer, and
P M Bouloux
November 2004,
Rheumatology (Oxford, England),
G A Roberts, and
E Eren, and
H Sinclair, and
M Pelling, and
A Burns, and
R Bradford, and
R Maurice-Williams, and
C M Black, and
N Finer, and
P M Bouloux
January 2008,
Pituitary,
