Biomaterial Database

Potentiometric determination of ephedrine hydrochloride using plastic membrane ion-selective electrode. 1993

M M Zareh, and Y M Issa, and A F Shoukry, and R E Shohaib

Chemistry Department, Faculty of Science, Zagazig University, Egypt.

A plastic membrane electrode based on phenylephrine-tetraphenylborate ion association shows a Nernstian response to both ephedrinium (Ep+) and silver (Ag+) cations over the concentration ranges 2 x 10(-5)-10(-1) M and 10(-5)-10(-1) M for Ep+ and Ag+, respectively. The performance characteristics of the electrode were investigated. The electrode proved to be an excellent potentiometric sensor for the determination of Ep-hydrochloride in its pure solutions and pharmaceutical preparations using the extrapolation method and potentiometric titration using a standard solution of AgNO3.

UI	MeSH Term	Description	Entries
D008567	Membranes, Artificial	Artificially produced membranes, such as semipermeable membranes used in artificial kidney dialysis (RENAL DIALYSIS), monomolecular and bimolecular membranes used as models to simulate biological CELL MEMBRANES. These membranes are also used in the process of GUIDED TISSUE REGENERATION.	Artificial Membranes,Artificial Membrane,Membrane, Artificial
D010969	Plastics	Polymeric materials (usually organic) of large molecular weight which can be shaped by flow. Plastic usually refers to the final product with fillers, plasticizers, pigments, and stabilizers included (versus the resin, the homogeneous polymeric starting material). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)	Plastic
D011143	Polyvinyl Chloride	A polyvinyl resin used extensively in the manufacture of plastics, including medical devices, tubing, and other packaging. It is also used as a rubber substitute.	Chloroethylene Polymer,Polychloroethylene,Vinyl Chloride Polymer,Chloroethylene Homopolymer,Geon,PVC,Ultron,Viaflex,Vinylite,Chloride, Polyvinyl,Homopolymer, Chloroethylene,Polymer, Chloroethylene,Polymer, Vinyl Chloride
D011199	Potentiometry	Solution titration in which the end point is read from the electrode-potential variations with the concentrations of potential determining ions. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
D004563	Electrochemistry	The study of chemical changes resulting from electrical action and electrical activity resulting from chemical changes.	Electrochemistries
D004809	Ephedrine	A phenethylamine found in EPHEDRA SINICA. PSEUDOEPHEDRINE is an isomer. It is an alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine. It has been used for asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. It has become less extensively used with the advent of more selective agonists.	Ephedrine Hydrochloride,Ephedrine Renaudin,Ephedrine Sulfate,Erythro Isomer of Ephedrine,Sal-Phedrine,Ephedrine Erythro Isomer,Hydrochloride, Ephedrine,Renaudin, Ephedrine,Sal Phedrine,SalPhedrine,Sulfate, Ephedrine
D006863	Hydrogen-Ion Concentration	The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH	pH,Concentration, Hydrogen-Ion,Concentrations, Hydrogen-Ion,Hydrogen Ion Concentration,Hydrogen-Ion Concentrations
D013775	Tetraphenylborate	An anionic compound that is used as a reagent for determination of potassium, ammonium, rubidium, and cesium ions. It also uncouples oxidative phosphorylation and forms complexes with biological materials, and is used in biological assays.	Sodium Tetraphenylborate,Tetraphenylboron Sodium,Kalignost,Tetraphenylborate Sodium Salt,Tetraphenylborate, Ammonium Salt,Tetraphenylborate, Barium Salt (2:1),Tetraphenylborate, Potassium Salt,Tetraphenylboron,Ammonium Salt Tetraphenylborate,Potassium Salt Tetraphenylborate,Sodium Salt, Tetraphenylborate,Sodium, Tetraphenylboron,Tetraphenylborate, Sodium
D017736	Ion-Selective Electrodes	Electrodes which can be used to measure the concentration of particular ions in cells, tissues, or solutions.	Electrodes, Ion-Selective,Ion Selective Electrode,Ion-Sensitive Electrode,Ion-Sensitive Electrodes,Electrode, Ion Selective,Electrode, Ion-Selective,Electrode, Ion-Sensitive,Electrodes, Ion Selective,Electrodes, Ion-Sensitive,Ion Selective Electrodes,Ion Sensitive Electrode,Ion Sensitive Electrodes,Ion-Selective Electrode,Selective Electrode, Ion,Selective Electrodes, Ion