Biomaterial Database

A continuous reactor system for production of lactulose. 1994

M Kozempel, and M Kurantz

Engineering Science Unit, United States Department of Agriculture, Philadelphia, Pennsylvania 19118.

A continuous reactor process was developed to produce lactulose from lactose. A system of two CSTRs in series with a tubular finishing reactor gave conversion to lactulose of about 76%. The reactors ran at 71-75 degrees C with a volumetric hold-up in the CSTRs of 22.7 dm3 and in the tubular reactor of 2.6 dm3. Each CSTR had a nominal residence time of 44 min. The flow rate was 0.53 dm3 min-1.

UI	MeSH Term	Description	Entries
D007700	Kinetics	The rate dynamics in chemical or physical systems.
D007785	Lactose	A disaccharide of GLUCOSE and GALACTOSE in human and cow milk. It is used in pharmacy for tablets, in medicine as a nutrient, and in industry.	Anhydrous Lactose,Lactose, Anhydrous
D007792	Lactulose	A synthetic disaccharide used in the treatment of constipation and hepatic encephalopathy. It has also been used in the diagnosis of gastrointestinal disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p887)	Amivalex,Duphalac,Normase
D001888	Boric Acids	Inorganic and organic derivatives of boric acid either B(OH)3 or, preferably H3BO3.	Acids, Boric
D001709	Biotechnology	Body of knowledge related to the use of organisms, cells or cell-derived constituents for the purpose of developing products which are technically, scientifically and clinically useful. Alteration of biologic function at the molecular level (i.e., GENETIC ENGINEERING) is a central focus; laboratory methods used include TRANSFECTION and CLONING technologies, sequence and structure analysis algorithms, computer databases, and gene and protein structure function analysis and prediction.	Biotechnologies