Biomaterial Database

Prediction of fetal macrosomia using humeral soft tissue thickness. 1995

A K Sood, and M Yancey, and D Richards

Department of Obstetrics and Gynecology, University of Florida College of Medicine, Gainesville, USA.

OBJECTIVE To determine the usefulness of an objective assessment of humeral soft tissue thickness in estimating birth weight in a population at risk for macrosomia. METHODS Shortly before delivery, ultrasound examinations were performed on 95 women at risk of having macrosomic infants. In each case, the fetal humeral soft tissue thickness (the distance between the outer edge of the humerus to the skin surface on transverse views of the upper arm) was measured three times, and an average was taken. RESULTS The humeral soft tissue thickness correlated significantly with birth weight (R2 = 0.40, P < .001) and ponderal index (R2 = 0.20, P = .02). The humeral soft tissue thickness was significantly higher in macrosomic infants (P < .001), in those with an abnormally high ponderal index (P = .02), and in infants whose deliveries were complicated by shoulder dystocia (P = .05). There was no apparent effect of maternal diabetes on the humeral soft tissue thickness. The humeral soft tissue thickness was more sensitive in predicting macrosomia than was the ultrasound-estimated fetal weight (88 versus 71%), but less specific (75 versus 91%). CONCLUSIONS The humeral soft tissue thickness correlates with birth weight. However, its clinical use compared with other predictors remains to be defined.

UI	MeSH Term	Description	Entries
D011237	Predictive Value of Tests	In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.	Negative Predictive Value,Positive Predictive Value,Predictive Value Of Test,Predictive Values Of Tests,Negative Predictive Values,Positive Predictive Values,Predictive Value, Negative,Predictive Value, Positive
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D012044	Regression Analysis	Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.	Regression Diagnostics,Statistical Regression,Analysis, Regression,Analyses, Regression,Diagnostics, Regression,Regression Analyses,Regression, Statistical,Regressions, Statistical,Statistical Regressions
D001724	Birth Weight	The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms.	Birthweight,Birth Weights,Birthweights,Weight, Birth,Weights, Birth
D005260	Female		Females
D005320	Fetal Macrosomia	A condition of fetal overgrowth defined as BIRTH WEIGHT greater than 4,000 grams, regardless of gestational age. It is commonly seen in GESTATIONAL DIABETES; PROLONGED PREGNANCY; and pregnancies complicated by pre-existing diabetes mellitus.	Macrosomia, Fetal,Fetal Macrosomias,Macrosomias, Fetal
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006811	Humerus	Bone in humans and primates extending from the SHOULDER JOINT to the ELBOW JOINT.	Humeri,Greater Tubercle,Humeral Greater Tuberosity,Humeral Lesser Tuberosity,Lesser Tubercle,Olecranon Fossa,Olecranon Fossi,Greater Tubercles,Greater Tuberosities, Humeral,Greater Tuberosity, Humeral,Humeral Greater Tuberosities,Humeral Lesser Tuberosities,Lesser Tubercles,Lesser Tuberosities, Humeral,Lesser Tuberosity, Humeral,Tubercle, Greater,Tubercles, Greater
D000273	Adipose Tissue	Specialized connective tissue composed of fat cells (ADIPOCYTES). It is the site of stored FATS, usually in the form of TRIGLYCERIDES. In mammals, there are two types of adipose tissue, the WHITE FAT and the BROWN FAT. Their relative distributions vary in different species with most adipose tissue being white.	Fatty Tissue,Body Fat,Fat Pad,Fat Pads,Pad, Fat,Pads, Fat,Tissue, Adipose,Tissue, Fatty
D001132	Arm	The superior part of the upper extremity between the SHOULDER and the ELBOW.	Brachium,Upper Arm,Arm, Upper,Arms,Arms, Upper,Brachiums,Upper Arms