Efficacy of Cymelarsan in the treatment of natural chronic Trypanosoma evansi infection in camels in the Sudan. 1994

M M Musa, and A M Abdoon, and B T Nasir, and Y I Salim, and A Y Abdel-Rahman, and A M Shommein
Tsetse and Trypanosomiasis Control Department, Central Veterinary Research Administration, Khartoum, Soudan.

The efficacy of Cymelarsan, administered by intramuscular (i/m) injection in the treatment of chronic cases of camel trypanosomosis due to Trypanosoma evansi, was tested under controlled laboratory conditions. It was confirmed that Cymelarsan is a safe drug for use in dromedary camels when administered i/m at dose rates of 0.25 or 0.50 mg/kg body weight. During the 90 days post-treatment no relapses occurred at either dose rate. Hence, the drug was found to be fully effective against the chronic form of the natural disease. A dose of 0.25 mg/kg body weight of Cymelarsan given i/m is recommended.

UI MeSH Term Description Entries
D002162 Camelus Two-toed, hoofed mammals with four legs, a big-lipped snout, and a humped back belonging to the family Camelidae. They are native to North Africa, and Western and Central Asia. Camels,Dromedary,Bactrian Camels,Bractrian Camels,Camelus bactrianus,Camelus dromedarius,Bactrian Camel,Bractrian Camel,Camel,Camel, Bactrian,Camel, Bractrian,Camels, Bactrian,Camels, Bractrian,Dromedaries
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001152 Arsenicals Inorganic or organic compounds that contain arsenic. Arsenic Compounds,Compounds, Arsenic
D013397 Sudan A country in northeastern Africa. The capital is Khartoum. Republic of the Sudan
D014344 Trypanocidal Agents Agents destructive to the protozoal organisms belonging to the suborder TRYPANOSOMATINA. Trypanocidal Drugs,Trypanocides,Trypanosomicidal Agents,Trypanosomicides,Agents, Trypanocidal,Agents, Trypanosomicidal,Drugs, Trypanocidal
D014353 Trypanosomiasis, African A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces "African sleeping sickness." Nagana is a rapidly fatal trypanosomiasis of horses and other animals. African Sleeping Sickness,Nagana,African Trypanosomiasis,African Sleeping Sicknesses,African Trypanosomiases,Sickness, African Sleeping,Sicknesses, African Sleeping,Sleeping Sickness, African,Sleeping Sicknesses, African,Trypanosomiases, African

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