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129 cases of non-malignant gastric lesions and 171 cases of gastric carcinoma were studied immunohistochemically for pepsinogen C. PgC was constantly expressed at the bottom of the gastric glands irrespective of the disease. PgC was much more frequently observed in cancer patients (p < 0.001). PgC-positive were carcinoma tissues (38%), particularly of the intestinal type (53.4%), but also in mixed (40%) and diffuse (15.5%) types. PgC-negative carcinomas were more frequently observed in combination with PgC-positive areas of the surface epithelium (p < 0.001) and intestinal metaplasia (p < 0.05). PgC-positive dysplastic foci were observed in both groups of PgC-positive and PgC-negative malignant tumours.
G A Frank, and
K K Pugachev, and
T A Belous, and
I B Shimbireva, and
V I Fofanov, and
A N Petrov, and
K P Shabalov
January 1988,
Eksperimental'naia onkologiia,
G A Frank, and
K K Pugachev, and
T A Belous, and
I B Shimbireva, and
V I Fofanov, and
A N Petrov, and
K P Shabalov
September 1996,
Journal of biochemistry,
G A Frank, and
K K Pugachev, and
T A Belous, and
I B Shimbireva, and
V I Fofanov, and
A N Petrov, and
K P Shabalov
January 1988,
Zeitschrift fur mikroskopisch-anatomische Forschung,
G A Frank, and
K K Pugachev, and
T A Belous, and
I B Shimbireva, and
V I Fofanov, and
A N Petrov, and
K P Shabalov
February 1991,
European journal of cell biology,
G A Frank, and
K K Pugachev, and
T A Belous, and
I B Shimbireva, and
V I Fofanov, and
A N Petrov, and
K P Shabalov
November 1976,
Journal of biochemistry,
G A Frank, and
K K Pugachev, and
T A Belous, and
I B Shimbireva, and
V I Fofanov, and
A N Petrov, and
K P Shabalov
October 1987,
Journal of anatomy,
G A Frank, and
K K Pugachev, and
T A Belous, and
I B Shimbireva, and
V I Fofanov, and
A N Petrov, and
K P Shabalov
December 1963,
The American journal of physiology,
G A Frank, and
K K Pugachev, and
T A Belous, and
I B Shimbireva, and
V I Fofanov, and
A N Petrov, and
K P Shabalov
May 1991,
The Italian journal of gastroenterology,
G A Frank, and
K K Pugachev, and
T A Belous, and
I B Shimbireva, and
V I Fofanov, and
A N Petrov, and
K P Shabalov
January 1967,
Arkhiv patologii,
G A Frank, and
K K Pugachev, and
T A Belous, and
I B Shimbireva, and
V I Fofanov, and
A N Petrov, and
K P Shabalov
February 1988,
Nihon hoigaku zasshi = The Japanese journal of legal medicine,
