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We have measured the H type 1, Le(a) and Le(b) antigens in the saliva from 129 Japanese individuals by a time-resolved europium ion fluorometric immunoassay using artificial antigen-albumin complexes as the reference substances. We confirmed that the amount of Le(b) was larger than that of Le(a) in the saliva from secretors (Le(a-b+)) and vice versa in the saliva from nonsecretors (Le(a+b-)). Unexpectedly, we discovered appreciable amounts of Le(b) with small amounts of H type 1 in the saliva from the nonsecretors. The concentration of Le(b) was about 10, 6 and 35% of the concentration of the Le(a) in the saliva from the nonsecretors of the A, B and O groups, respectively. The possible formation of Le(b) from Le(a), in addition to the formation of Le(b) from H type 1, in the salivary glands is discussed.
B Wang, and
K Akiyama, and
H Kimura
January 1983,
Vox sanguinis,
B Wang, and
K Akiyama, and
H Kimura
January 1972,
Igaku to seibutsugaku. Medicine and biology,
B Wang, and
K Akiyama, and
H Kimura
September 1972,
Jinrui idengaku zasshi. The Japanese journal of human genetics,
B Wang, and
K Akiyama, and
H Kimura
January 1972,
Igaku to seibutsugaku. Medicine and biology,
B Wang, and
K Akiyama, and
H Kimura
February 1970,
Annals of the New York Academy of Sciences,
B Wang, and
K Akiyama, and
H Kimura
September 1972,
Jinrui idengaku zasshi. The Japanese journal of human genetics,
B Wang, and
K Akiyama, and
H Kimura
January 1994,
Virchows Archiv : an international journal of pathology,
B Wang, and
K Akiyama, and
H Kimura
January 1994,
Vox sanguinis,
B Wang, and
K Akiyama, and
H Kimura
April 1972,
Biulleten' eksperimental'noi biologii i meditsiny,
B Wang, and
K Akiyama, and
H Kimura
July 1988,
Laboratory investigation; a journal of technical methods and pathology,
