Biomaterial Database

[Preventive anti-D after massive fetomaternal hemorrhage]. 1995

E Strobel, and G Hofmeister, and J Wüllenweber

Institut für Medizinische Mikrobiologie, Immunologie und Krankenhaushygiene, Städtisches Krankenhaus München-Schwabing.

In the 36th week of gestation intrauterine death of both twins occurred in a 31-year old primigravida. The examination of the C- and the D-antigen of the mother's blood (result of previous testing: AB Rhesus negative) immediately before delivery showed a mixed field agglutination which pointed to a fetomaternal macrotransfusion. Fetal haemoglobin in the mother's circulation was 7.8% of her total haemoglobin, so that a fetomaternal haemorrhage of about 440 ml whole blood had to be suspected. For Rhesus-prophylaxis 17 standard doses of anti-D-immunoglobulin were administered intramuscularly distributed over 4 days. No adverse effects were seen; fetal haemoglobin dropped to 2.0% 5 days and to 0.1% 15 days after the beginning of the treatment. A control examination after 9 months showed no signs of a Rhesus-(D)-sensitisation of the patient.

UI	MeSH Term	Description	Entries
D007231	Infant, Newborn	An infant during the first 28 days after birth.	Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D007273	Injections, Intramuscular	Forceful administration into a muscle of liquid medication, nutrient, or other fluid through a hollow needle piercing the muscle and any tissue covering it.	Intramuscular Injections,Injection, Intramuscular,Intramuscular Injection
D007518	Isoantibodies	Antibodies from an individual that react with ISOANTIGENS of another individual of the same species.	Alloantibodies
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D011272	Pregnancy, Multiple	The condition of carrying two or more FETUSES simultaneously.	Multiple Pregnancy,Multiple Pregnancies,Pregnancies, Multiple
D005260	Female		Females
D005313	Fetal Death	Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH.	Fetal Mummification,Fetal Demise,Death, Fetal,Deaths, Fetal,Demise, Fetal,Fetal Deaths,Mummification, Fetal
D005331	Fetomaternal Transfusion	Transplacental passage of fetal blood into the circulation of the maternal organism. (Dorland, 27th ed)	Hemorrhage, Fetomaternal,Fetomaternal Hemorrhage,Fetomaternal Hemorrhages,Fetomaternal Transfusions,Hemorrhages, Fetomaternal,Transfusion, Fetomaternal,Transfusions, Fetomaternal
D005500	Follow-Up Studies	Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.	Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man