Biomaterial Database

[Polymer-containing eyedrops. III. Surface tension of polymer solutions]. 1995

E Ugriné Hunyadvári, and G Tóthné Kiss, and C Kissné Koczka

Szent-Györgyi Albert Orvostudományi Egyetem Gyógyszertechnológiai Intézet, Szeged.

Therapeutical effect of ophthalmological solutions is markedly influenced by their surface tension which is also responsible for the irritating effect of the eye drop. Authors studied the effect of different polymers on surface tension. They found that each of the water soluble polymers studied decreased the surface tension of solutions against air. This surface tension decreasing effect is independent from the concentration of the solution. Its value is slightly influenced by the pH of the solution, while it is increased by its electrolyte content.

UI	MeSH Term	Description	Entries
D009883	Ophthalmic Solutions	Sterile solutions that are intended for instillation into the eye. It does not include solutions for cleaning eyeglasses or CONTACT LENS SOLUTIONS.	Eye Drop,Eyedrop,Eyedrops,Ophthalmic Solution,Eye Drops,Drop, Eye,Drops, Eye,Solution, Ophthalmic,Solutions, Ophthalmic
D011108	Polymers	Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).	Polymer
D004573	Electrolytes	Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)	Electrolyte
D006863	Hydrogen-Ion Concentration	The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH	pH,Concentration, Hydrogen-Ion,Concentrations, Hydrogen-Ion,Hydrogen Ion Concentration,Hydrogen-Ion Concentrations
D013500	Surface Tension	The force acting on the surface of a liquid, tending to minimize the area of the surface. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Interfacial Force,Interfacial Tension,Surface Tensions,Tension, Surface,Tensions, Surface