Vertebral hyperostosis and diabetes mellitus: a case-control study. 1995

A Daragon, and O Mejjad, and P Czernichow, and J P Louvel, and O Vittecoq, and A Durr, and X Le Loët
Department of Rheumatology, CHU de Rouen, France.

OBJECTIVE To compare glucose metabolism in patients with vertebral hyperostosis (VH), with that in control patients. METHODS We studied 50 patients aged 60 years or more who had VH according to Resnick's criteria, and 50 control patients without VH, matched for sex, age, weight and height. Plasma glucose was evaluated before and 120 minutes after ingestion of 75 g glucose. World Health Organisation criteria for diabetes mellitus (DM) were used. Radiographs of the pelvis and thoracic and lumbar spine were performed and read blind by two physicians. RESULTS Statistical analysis showed no difference between cases and control patients for prevalence of DM, and plasma glucose at 0 and 120 minutes. CONCLUSIONS These data suggest that glucoregulation in patients with VH does not differ from that in matched controls.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D003920 Diabetes Mellitus A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
D004057 Hyperostosis, Diffuse Idiopathic Skeletal A disease of elderly men characterized by large osteophytes that bridge vertebrae and ossification of ligaments and tendon insertions. Diffuse Idiopathic Skeletal Hyperostosis,Forestier Disease,Vertebral Ankylosing Hyperostosis,Ankylosing Vertebral Hyperostosis with Tylosis,Forestier's Disease,Forestier-Rotes Disease,Ankylosing Hyperostoses, Vertebral,Ankylosing Hyperostosis, Vertebral,Disease, Forestier,Disease, Forestier's,Disease, Forestier-Rotes,Forestier Rotes Disease,Forestiers Disease,Hyperostoses, Vertebral Ankylosing,Hyperostosis, Vertebral Ankylosing,Vertebral Ankylosing Hyperostoses
D005260 Female Females
D005947 Glucose A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement. Dextrose,Anhydrous Dextrose,D-Glucose,Glucose Monohydrate,Glucose, (DL)-Isomer,Glucose, (alpha-D)-Isomer,Glucose, (beta-D)-Isomer,D Glucose,Dextrose, Anhydrous,Monohydrate, Glucose
D005951 Glucose Tolerance Test A test to determine the ability of an individual to maintain HOMEOSTASIS of BLOOD GLUCOSE. It includes measuring blood glucose levels in a fasting state, and at prescribed intervals before and after oral glucose intake (75 or 100 g) or intravenous infusion (0.5 g/kg). Intravenous Glucose Tolerance,Intravenous Glucose Tolerance Test,OGTT,Oral Glucose Tolerance,Oral Glucose Tolerance Test,Glucose Tolerance Tests,Glucose Tolerance, Oral
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D000369 Aged, 80 and over Persons 80 years of age and older. Oldest Old

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