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The majority of computer tomography stereotactic biopsy lesions enhance after administration of intravenous contrast, whereas patients with nonenhancing lesions are often followed conservatively or undergo craniotomies. There are few studies showing the effectiveness of stereotactic biopsies of nonenhancing cerebral lesions. Stereotactic biopsies were performed on 19 patients with lesions that did not enhance on CT after intravenous contrast. Pathological diagnoses were made in 90% (17/19) of patients. Four HIV-positive patients had progressive multifocal leukoencephalopathy, 11 patients had gliomas (4 astrocytomas, 6 anaplastic astrocytomas, and 1 ganglioma), 1 had multiple sclerosis, and 1 had herpes encephalitis. In 2 patients multiple biopsies revealed only gliosis. There was no morbidity or mortality. Stereotactic biopsies for nonenhancing brain lesions have a high diagnostic yield and can favorably alter the treatment course.
M J Perez-Cruet, and
L Adelman, and
M Anderson, and
P A Roth, and
A M Ritter, and
S C Saris
August 1994,
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M J Perez-Cruet, and
L Adelman, and
M Anderson, and
P A Roth, and
A M Ritter, and
S C Saris
April 1998,
Chinese medical journal,
M J Perez-Cruet, and
L Adelman, and
M Anderson, and
P A Roth, and
A M Ritter, and
S C Saris
January 2008,
Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association,
M J Perez-Cruet, and
L Adelman, and
M Anderson, and
P A Roth, and
A M Ritter, and
S C Saris
March 2002,
The Journal of small animal practice,
M J Perez-Cruet, and
L Adelman, and
M Anderson, and
P A Roth, and
A M Ritter, and
S C Saris
August 1987,
American journal of clinical oncology,
M J Perez-Cruet, and
L Adelman, and
M Anderson, and
P A Roth, and
A M Ritter, and
S C Saris
January 1992,
The Journal of the Kentucky Medical Association,
M J Perez-Cruet, and
L Adelman, and
M Anderson, and
P A Roth, and
A M Ritter, and
S C Saris
January 1999,
Folia neuropathologica,
M J Perez-Cruet, and
L Adelman, and
M Anderson, and
P A Roth, and
A M Ritter, and
S C Saris
July 1993,
Southern medical journal,
M J Perez-Cruet, and
L Adelman, and
M Anderson, and
P A Roth, and
A M Ritter, and
S C Saris
January 1986,
Diagnostic cytopathology,
M J Perez-Cruet, and
L Adelman, and
M Anderson, and
P A Roth, and
A M Ritter, and
S C Saris
January 1994,
Stereotactic and functional neurosurgery,
