-transparent.png){kind=logo}
A girl aged 1 year and 2 months with hypomelanosis of Ito was reported. She suffered from intractable epileptic seizures since the second day after birth. Characteristic bizarre hypopigmented skin lesions were seen on her left shoulder and extended in a linear fashion to the flexion side of the left upper extremity. Brain MRI revealed diffuse enlargement of the left hemisphere, dilatation of the left lateral ventricle, and neuronal migration anomalies, indicating hemimegalencephaly. The types of her seizures were secondarily generalized or unilateral initially, followed by infantile spasms at 1.5 month. Around 4 months of age, frequent partial seizures appeared. Her seizures were intractable despite vigorous anticonvulsant therapy. As patients with hypomelanosis of Ito are frequently associated with neurological abnormalities, brain MRI studies were thought to be essential in detecting central nervous system anomalies, particularly in the presence of early onset intractable seizures.
T Tagawa, and
K Otani, and
Y Futagi, and
H Arai, and
S Mushiake, and
M Nakayama, and
Y Morita
November 2009,
Dermatology online journal,
T Tagawa, and
K Otani, and
Y Futagi, and
H Arai, and
S Mushiake, and
M Nakayama, and
Y Morita
May 1988,
Acta paediatrica Scandinavica,
T Tagawa, and
K Otani, and
Y Futagi, and
H Arai, and
S Mushiake, and
M Nakayama, and
Y Morita
September 1997,
Pediatric neurology,
T Tagawa, and
K Otani, and
Y Futagi, and
H Arai, and
S Mushiake, and
M Nakayama, and
Y Morita
November 1990,
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery,
T Tagawa, and
K Otani, and
Y Futagi, and
H Arai, and
S Mushiake, and
M Nakayama, and
Y Morita
March 2014,
Journal of child neurology,
T Tagawa, and
K Otani, and
Y Futagi, and
H Arai, and
S Mushiake, and
M Nakayama, and
Y Morita
January 1996,
Pediatric radiology,
T Tagawa, and
K Otani, and
Y Futagi, and
H Arai, and
S Mushiake, and
M Nakayama, and
Y Morita
January 2006,
Pediatric neurology,
T Tagawa, and
K Otani, and
Y Futagi, and
H Arai, and
S Mushiake, and
M Nakayama, and
Y Morita
July 1992,
European child & adolescent psychiatry,
T Tagawa, and
K Otani, and
Y Futagi, and
H Arai, and
S Mushiake, and
M Nakayama, and
Y Morita
October 2004,
Indian journal of pediatrics,
T Tagawa, and
K Otani, and
Y Futagi, and
H Arai, and
S Mushiake, and
M Nakayama, and
Y Morita
January 1997,
Neurologia (Barcelona, Spain),
