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OBJECTIVE To evaluate the efficacy of color Doppler ultrasonography as the predictor of malignant ovarian tumors and to compare the results with CA 125 levels and ultrasonographic morphological patterns. METHODS We compared color Doppler ultrasound with sonographic findings and serum CA 125 levels for predicting ovarian malignancy in 16 patients with malignant and 12 patients with benign ovarian tumors. RESULTS There was a significant difference in pulsatility index (PI) value of ovarian vessel between benign and malignant tumors (2.42 +/- 0.67 for benign and 1.35 +/- 0.78 for malignant, respectively, P < 0.01). The specificity of morphological findings and CA 125 was lower than that of PI measurements, but sensitivity was not different between the three methods. In addition, the combination of color Doppler and CA 125 or morphological assessments resulted in a sensitivity of 100% and a negative predictive value of 100%, respectively. CONCLUSIONS PI measurements by transvaginal color Doppler ultrasound combined with CA 125 levels or morphological findings could be an accurate and appropriate screening method for ovarian tumors.
K Sengoku, and
T Satoh, and
S Saitoh, and
M Abe, and
M Ishikawa
December 1992,
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine,
K Sengoku, and
T Satoh, and
S Saitoh, and
M Abe, and
M Ishikawa
July 1992,
Gynecologic oncology,
K Sengoku, and
T Satoh, and
S Saitoh, and
M Abe, and
M Ishikawa
December 1992,
Obstetrics and gynecology,
K Sengoku, and
T Satoh, and
S Saitoh, and
M Abe, and
M Ishikawa
January 2002,
Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti,
K Sengoku, and
T Satoh, and
S Saitoh, and
M Abe, and
M Ishikawa
January 2003,
European journal of gynaecological oncology,
K Sengoku, and
T Satoh, and
S Saitoh, and
M Abe, and
M Ishikawa
July 1994,
Fertility and sterility,
K Sengoku, and
T Satoh, and
S Saitoh, and
M Abe, and
M Ishikawa
June 1993,
Obstetrics and gynecology,
K Sengoku, and
T Satoh, and
S Saitoh, and
M Abe, and
M Ishikawa
September 1999,
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics,
K Sengoku, and
T Satoh, and
S Saitoh, and
M Abe, and
M Ishikawa
January 1993,
Journal of clinical ultrasound : JCU,
K Sengoku, and
T Satoh, and
S Saitoh, and
M Abe, and
M Ishikawa
July 1991,
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology,
