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A comparative clinical study of idiopathic portal hypertension, extrahepatic portal vein thrombosis, and cirrhosis. 1994

H Orozco, and T Takahashi, and G Garcia-Tsao, and M A Mercado, and E Prado, and R Nava
Department of Surgery, Instituto Nacional de la Nutricion Salvador Zubiran, Mexico City, Mexico.

The relationship between idiopathic portal hypertension (IPH) and extrahepatic portal vein thrombosis (EPVT) remains controversial. In a retrospective study, we compared the clinical features of 21 patients with IPH, 27 with EPVT, and 38 with liver cirrhosis (LC). The variables with statistical difference between IPH and EPVT were age (38 +/- 17 years versus 29 +/- 14, respectively; p < 0.05), and 5-year survival (72 versus 92%, respectively; p < 0.05). The other clinical and laboratory variables had similar distribution in IPH and EPVT. LC patients were older than those in the other groups (48 +/- 13 years, p < 0.05), and had a poorer 5-year survival (60%, p < 0.05). Furthermore, LC patients had clinical features of liver failure in a higher proportion than the other groups did. The results suggest that IPH, EPVT, and LC are separate clinical entities.

UI MeSH Term Description Entries
D006975 Hypertension, Portal Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN. Cruveilhier-Baumgarten Disease,Cruveilhier-Baumgarten Syndrome,Cruveilhier Baumgarten Disease,Cruveilhier Baumgarten Syndrome,Disease, Cruveilhier-Baumgarten,Portal Hypertension,Portal Hypertensions,Syndrome, Cruveilhier-Baumgarten
D008103 Liver Cirrhosis Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules. Cirrhosis, Liver,Fibrosis, Liver,Hepatic Cirrhosis,Liver Fibrosis,Cirrhosis, Hepatic
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011169 Portal Vein A short thick vein formed by union of the superior mesenteric vein and the splenic vein. Portal Veins,Vein, Portal,Veins, Portal
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000367 Age Factors Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time. Age Reporting,Age Factor,Factor, Age,Factors, Age

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