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In a group of 94 patients with a histologically verified medullary thyroid carcinoma were 59 patients with the sporadic form and 35 patients with the familial form. After radical surgery and subsequent actinotherapy in all patients the values of immunoreactive calcitonin were monitored along with the sonographic examination. In all with calcified thyroid residues confirmed on sonography, or when metastases were detected in the liver, elevated or high levels of immunoreactive calcitonin were found. The authors emphasize the importance of this examination for the early detection of relapses of medullary thyroid carcinoma.
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