Biomaterial Database

A molecular dissection of spatial patterning in the olfactory system. 1994

K J Ressler, and S L Sullivan, and L B Buck

Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115.

The identification and cloning of genes encoding odorant receptors has provided molecular probes with which to examine the molecular mechanisms and organizational strategies underlying olfactory information processing. Recent studies using odorant receptor genes have revealed unexpected patterns of expression that provide new insights into how information may be organized in the nose and in the axonal projection from the nose to the brain.

UI	MeSH Term	Description	Entries
D008969	Molecular Sequence Data	Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.	Sequence Data, Molecular,Molecular Sequencing Data,Data, Molecular Sequence,Data, Molecular Sequencing,Sequencing Data, Molecular
D009831	Olfactory Mucosa	That portion of the nasal mucosa containing the sensory nerve endings for SMELL, located at the dome of each NASAL CAVITY. The yellow-brownish olfactory epithelium consists of OLFACTORY RECEPTOR NEURONS; brush cells; STEM CELLS; and the associated olfactory glands.	Olfactory Epithelium,Olfactory Membrane,Epithelium, Olfactory,Membrane, Olfactory,Membranes, Olfactory,Mucosa, Olfactory,Olfactory Membranes
D009833	Olfactory Pathways	Set of nerve fibers conducting impulses from olfactory receptors to the cerebral cortex. It includes the OLFACTORY NERVE; OLFACTORY BULB; OLFACTORY TRACT; OLFACTORY TUBERCLE; ANTERIOR PERFORATED SUBSTANCE; and OLFACTORY CORTEX.	Olfactory Pathway,Pathway, Olfactory,Pathways, Olfactory
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000595	Amino Acid Sequence	The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.	Protein Structure, Primary,Amino Acid Sequences,Sequence, Amino Acid,Sequences, Amino Acid,Primary Protein Structure,Primary Protein Structures,Protein Structures, Primary,Structure, Primary Protein,Structures, Primary Protein
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012903	Smell	The ability to detect scents or odors, such as the function of OLFACTORY RECEPTOR NEURONS.	Olfaction,Sense of Smell,Smell Sense
D018035	Receptors, Odorant	Proteins, usually projecting from the cilia of olfactory receptor neurons, that specifically bind odorant molecules and trigger responses in the neurons. The large number of different odorant receptors appears to arise from several gene families or subfamilies rather than from DNA rearrangement.	Odorant Receptors,Olfactory Receptor Proteins,Odor Receptor Protein,Odorant Receptor,Olfactory Receptor,Olfactory Receptor Protein,Olfactory Receptors,Receptor Proteins, Odorant,Receptor Proteins, Olfactory,Odorant Receptor Proteins,Protein, Odor Receptor,Protein, Olfactory Receptor,Proteins, Odorant Receptor,Proteins, Olfactory Receptor,Receptor Protein, Odor,Receptor Protein, Olfactory,Receptor, Odorant,Receptor, Olfactory,Receptors, Olfactory