[Circulating thrombomodulin, a marker of acute systemic lupus erythematosus].
1994
P Mercie, and
M Seigneur, and
C Conri, and
J Constans, and
J L Pellegrin, and
M Longy-Boursier
UI
MeSH Term
Description
Entries
D008180
Lupus Erythematosus, Systemic
A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328
Adult
A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.
Adults
D018180
Thrombomodulin
A cell surface glycoprotein of endothelial cells that binds thrombin and serves as a cofactor in the activation of protein C and its regulation of blood coagulation.
Related Publications
P Mercie, and
M Seigneur, and
C Conri, and
J Constans, and
J L Pellegrin, and
M Longy-Boursier