Conformation therapy using a computer controlled telecobalt unit for advanced cervical carcinoma. 1994

L F Senanayake, and S L Sun, and C Collis, and A T Tate, and D B Skeggs, and T J Davy
Department of Radiotherapy and Oncology, Royal Free Hospital, London, UK.

This retrospective analysis evaluates the results of conformation radiotherapy for patients with advanced cervical carcinoma. Between January 1980 and September 1987, 16 patients with high common iliac/para-aortic node metastases from advanced carcinoma of the uterine cervix were treated using conformation radiotherapy. A large area from L1/L2 to the pelvis, with an average length of 23 cm, was treated to a total tumour dose of 5000-5500 cGy, with a daily tumour dose of 180-200 cGy in 28-30 daily fractions, using a computer controlled tracking cobalt unit (CCTCU). Before external beam irradiation, 11 patients underwent laparotomy/hysterectomy, seven were given chemotherapy and eight received brachytherapy. The preliminary results are encouraging. The actuarial 1-year, 3-year and 5-year survival rates after treatment were 81%, 44% and 37%, respectively. The locoregional control rate was 62.5%. None of the patients relapsed in the para-aortic nodes. All patients tolerated the large area of tracking irradiation therapy very well. None had any severe acute or delayed radiation complications. Use of the conformation radiotherapy technique to include the pelvic and para-aortic nodes has been shown to be an effective form of radiotherapy with minimal morbidity.

UI MeSH Term Description Entries
D008207 Lymphatic Metastasis Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. Lymph Node Metastasis,Lymph Node Metastases,Lymphatic Metastases,Metastasis, Lymph Node
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011867 Radioisotope Teletherapy A type of high-energy radiotherapy using a beam of gamma-radiation produced by a radioisotope source encapsulated within a teletherapy unit. Teleradioisotope Therapy,Teletherapy, Radioisotope,Therapy, Teleradioisotope
D011879 Radiotherapy Dosage The total amount of radiation absorbed by tissues as a result of radiotherapy. Dosage, Radiotherapy,Dosages, Radiotherapy,Radiotherapy Dosages
D011881 Radiotherapy, Computer-Assisted Computer systems or programs used in accurate computations for providing radiation dosage treatment to patients. Computer-Assisted Radiotherapy,Radiation Therapy, Computer-Assisted,Computer-Assisted Radiation Therapy,Computer Assisted Radiation Therapy,Computer Assisted Radiotherapy,Computer-Assisted Radiation Therapies,Computer-Assisted Radiotherapies,Radiation Therapies, Computer-Assisted,Radiation Therapy, Computer Assisted,Radiotherapies, Computer-Assisted,Radiotherapy, Computer Assisted,Therapies, Computer-Assisted Radiation,Therapy, Computer-Assisted Radiation
D002583 Uterine Cervical Neoplasms Tumors or cancer of the UTERINE CERVIX. Cancer of Cervix,Cancer of the Cervix,Cancer of the Uterine Cervix,Cervical Cancer,Cervical Neoplasms,Cervix Cancer,Cervix Neoplasms,Neoplasms, Cervical,Neoplasms, Cervix,Uterine Cervical Cancer,Cancer, Cervical,Cancer, Cervix,Cancer, Uterine Cervical,Cervical Cancer, Uterine,Cervical Cancers,Cervical Neoplasm,Cervical Neoplasm, Uterine,Cervix Neoplasm,Neoplasm, Cervix,Neoplasm, Uterine Cervical,Uterine Cervical Cancers,Uterine Cervical Neoplasm
D003037 Cobalt Radioisotopes Unstable isotopes of cobalt that decay or disintegrate emitting radiation. Co atoms with atomic weights of 54-64, except 59, are radioactive cobalt isotopes. Radioisotopes, Cobalt
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

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