The adherence of silicone oil to standard and heparin-coated PMMA intraocular lenses. 1994

M Batterbury, and D Wong, and R Williams, and R Bates
St Paul's Eye Unit, Royal Liverpool University Hospital, UK.

During combined cataract extraction and intraocular lens insertion in eyes undergoing removal of silicone oil, we noted that oil became adherent to the implant. This adhesion persisted post-operatively. Although patients seemed not to be symptomatic as a result of this effect, the oil interferes with the fundal examination. Since heparin-coated intraocular lenses are more hydrophilic than unmodified lenses, oil should spread less well on these lenses and therefore be less adherent. This study was conducted to test this hypothesis. Heparin-surface-modified and unmodified polymethylmethacrylate (PMMA) lenses were immersed in 1000 centistoke neat silicone oil and in an emulsion of silicone oil taken from a patient. The lenses were washed with saline solution in an attempt to remove adherent oil. The lenses were photographed for examination and qualitative comparison. It was found that both neat and emulsified silicone oil was strongly adherent to both surface-modified and unmodified lenses, and could not easily be washed off. The heparin-coated lenses showed a tendency for adherence of emulsified oil. It is concluded that heparin coating of intraocular lenses does not prevent, though may reduce, oil adherence. We recommend that care be taken to avoid contact between oil and implant during combined oil removal and cataract extraction.

UI MeSH Term Description Entries
D007910 Lenses, Intraocular Artificial implanted lenses. Implantable Contact Lens,Lens, Intraocular,Contact Lens, Implantable,Intraocular Lens,Intraocular Lenses,Lens, Implantable Contact
D008768 Methylmethacrylates The methyl esters of methacrylic acid that polymerize easily and are used as tissue cements, dental materials, and absorbent for biological substances.
D002387 Cataract Extraction The removal of a cataractous CRYSTALLINE LENS from the eye. Enzymatic Zonulolysis,Phakectomy,Cataract Extractions,Enzymatic Zonulolyses,Extraction, Cataract,Extractions, Cataract,Phakectomies,Zonulolyses, Enzymatic,Zonulolysis, Enzymatic
D006493 Heparin A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts. Heparinic Acid,alpha-Heparin,Heparin Sodium,Liquaemin,Sodium Heparin,Unfractionated Heparin,Heparin, Sodium,Heparin, Unfractionated,alpha Heparin
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000268 Adhesiveness A property of the surface of an object that makes it stick to another surface. Adhesivenesses
D012827 Silicone Oils Organic siloxanes which are polymerized to the oily stage. The oils have low surface tension and density less than 1. They are used in industrial applications and in the treatment of retinal detachment, complicated by proliferative vitreoretinopathy. Silicone Oil,Oil, Silicone

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