[An infrared spectrophotometric method for determining nitrous oxide and halothane in the air of operating rooms]. 1993

T Panev

Nitrous oxide and halothane are one of the most widely used anesthetics in the surgical practice. A spectrophotometric method in the infrared area is worked out for direct determination in gas phase simultaneously on nitrous oxide at 2236 cm-1 and on halothane at 813 cm-1 by means of 20 m gas cuvette. The sensitivity of the method for nitrous oxide is 20 mg/m3 and for halothane 5 mg/m3. The reproducibility of the method expressed as coefficient of variation is +/- 1-6%. The method is specific in the presence of other anesthesiological means. The air samples are taken in bags of Tedlar and depending on the sampling velocity the method can be used for recording the moment and average shift concentrations of nitrous oxide and halothane.

UI MeSH Term Description Entries
D009609 Nitrous Oxide Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream. Laughing Gas,Nitrogen Protoxide,Gas, Laughing,Oxide, Nitrous
D009873 Operating Rooms Facilities equipped for performing surgery. Operating Room,Room, Operating,Rooms, Operating
D006221 Halothane A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. NITROUS OXIDE is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. (From AMA Drug Evaluations Annual, 1994, p178) 1,1,1-Trifluoro-2-Chloro-2-Bromoethane,Fluothane,Ftorotan,Narcotan
D000395 Air Pollutants, Occupational Toxic air-borne matter related to work performed They are usually produced by the specific nature of the occupation. Occupational Air Pollutants,Pollutants, Occupational Air
D012680 Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) Specificity,Sensitivity,Specificity and Sensitivity
D013055 Spectrophotometry, Infrared Spectrophotometry in the infrared region, usually for the purpose of chemical analysis through measurement of absorption spectra associated with rotational and vibrational energy levels of molecules. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) IR Spectra,Infrared Spectrophotometry,IR Spectras,Spectra, IR

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