-transparent.png){kind=logo}
Numerical aberrations of chromosomes were investigated in oral tumors by using fluorescence in situ hybridization (F1SH) with 4 chromosome centromere-specific DNA probes. The hybridization signals of the centromere sequence were easily detected and counted within interphase nuclei as well as metaphase chromosomes. The number of hybridized signals for chromosome 17 significantly increased in oral malignant tumors compared to benign tumors, which had two spots as well as normal lymphocytes. Cell lines derived from oral squamous cell carcinoma also showed numerical aberrations of chromosomes 1, 4 and 11, in addition to chromosome 17. These findings suggested that numerical aberrations of chromosomes occur during the development of malignant tumors of the oral cavity.
T Tsuji, and
Y Mimura, and
K Maeda, and
M Ida, and
K Sasaki, and
F Shinozaki
April 1995,
British journal of urology,
T Tsuji, and
Y Mimura, and
K Maeda, and
M Ida, and
K Sasaki, and
F Shinozaki
January 1999,
Yi chuan xue bao = Acta genetica Sinica,
T Tsuji, and
Y Mimura, and
K Maeda, and
M Ida, and
K Sasaki, and
F Shinozaki
November 1996,
Journal of hepatology,
T Tsuji, and
Y Mimura, and
K Maeda, and
M Ida, and
K Sasaki, and
F Shinozaki
September 1996,
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology,
T Tsuji, and
Y Mimura, and
K Maeda, and
M Ida, and
K Sasaki, and
F Shinozaki
January 1997,
European journal of histochemistry : EJH,
T Tsuji, and
Y Mimura, and
K Maeda, and
M Ida, and
K Sasaki, and
F Shinozaki
August 1996,
International journal of radiation biology,
T Tsuji, and
Y Mimura, and
K Maeda, and
M Ida, and
K Sasaki, and
F Shinozaki
November 1997,
Cancer genetics and cytogenetics,
T Tsuji, and
Y Mimura, and
K Maeda, and
M Ida, and
K Sasaki, and
F Shinozaki
June 1998,
The Laryngoscope,
T Tsuji, and
Y Mimura, and
K Maeda, and
M Ida, and
K Sasaki, and
F Shinozaki
May 1967,
Casopis lekaru ceskych,
T Tsuji, and
Y Mimura, and
K Maeda, and
M Ida, and
K Sasaki, and
F Shinozaki
January 2004,
Anticancer research,
