Biomaterial Database

11 beta-Hydroxysteroid dehydrogenase: a relevant determinant of gluco- and mineralocorticoid-actions. 1994

F J Frey

Department of Medicine, University of Berne, Switzerland.

UI	MeSH Term	Description	Entries
D008901	Mineralocorticoids	A group of CORTICOSTEROIDS primarily associated with water and electrolyte balance. This is accomplished through the effect on ION TRANSPORT in renal tubules, resulting in retention of sodium and loss of potassium. Mineralocorticoid secretion is itself regulated by PLASMA VOLUME, serum potassium, and ANGIOTENSIN II.	Mineralocorticoid,Mineralocorticoid Effect,Mineralocorticoid Effects,Effect, Mineralocorticoid,Effects, Mineralocorticoid
D010902	Pituitary Gland	A small, unpaired gland situated in the SELLA TURCICA. It is connected to the HYPOTHALAMUS by a short stalk which is called the INFUNDIBULUM.	Hypophysis,Hypothalamus, Infundibular,Infundibular Stalk,Infundibular Stem,Infundibulum (Hypophysis),Infundibulum, Hypophyseal,Pituitary Stalk,Hypophyseal Infundibulum,Hypophyseal Stalk,Hypophysis Cerebri,Infundibulum,Cerebri, Hypophysis,Cerebrus, Hypophysis,Gland, Pituitary,Glands, Pituitary,Hypophyseal Stalks,Hypophyses,Hypophysis Cerebrus,Infundibular Hypothalamus,Infundibular Stalks,Infundibulums,Pituitary Glands,Pituitary Stalks,Stalk, Hypophyseal,Stalk, Infundibular,Stalks, Hypophyseal,Stalks, Infundibular
D005938	Glucocorticoids	A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.	Glucocorticoid,Glucocorticoid Effect,Glucorticoid Effects,Effect, Glucocorticoid,Effects, Glucorticoid
D006913	Hydroxysteroid Dehydrogenases	Enzymes of the oxidoreductase class that catalyze the dehydrogenation of hydroxysteroids. (From Enzyme Nomenclature, 1992) EC 1.1.-.	Hydroxysteroid Dehydrogenase,Dehydrogenase, Hydroxysteroid,Dehydrogenases, Hydroxysteroid
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D042842	11-beta-Hydroxysteroid Dehydrogenases	Hydroxysteroid dehydrogenases that catalyzes the reversible conversion of CORTISOL to the inactive metabolite CORTISONE. Enzymes in this class can utilize either NAD or NADP as cofactors.	11 beta-Hydroxysteroid Dehydrogenase,11-Hydroxysteroid Dehydrogenase,11B-Hydroxysteroid Dehydrogenase,11beta-Hydroxysteroid Dehydrogenase,Corticosteroid 11-Oxidoreductase,Corticosteroid 11-Reductase,Cortisone 11-Oxoreductase,11 Hydroxysteroid Dehydrogenase,11 beta Hydroxysteroid Dehydrogenase,11 beta Hydroxysteroid Dehydrogenases,11-Oxidoreductase, Corticosteroid,11-Oxoreductase, Cortisone,11-Reductase, Corticosteroid,11B Hydroxysteroid Dehydrogenase,11beta Hydroxysteroid Dehydrogenase,Corticosteroid 11 Oxidoreductase,Corticosteroid 11 Reductase,Cortisone 11 Oxoreductase,Dehydrogenase, 11 beta-Hydroxysteroid,Dehydrogenase, 11-Hydroxysteroid,Dehydrogenase, 11B-Hydroxysteroid,Dehydrogenase, 11beta-Hydroxysteroid,Dehydrogenases, 11-beta-Hydroxysteroid,beta-Hydroxysteroid Dehydrogenase, 11