Acute renal failure in a case of fatal chromic acid poisoning. 1994

P P Varma, and V Jha, and A K Ghosh, and K Joshi, and V Sakhuja
Department of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Despite its frequent use in industry, acute poisoning by chromic acid has very rarely been reported. We report a patient who developed massive gastrointestinal hemorrhage, acute renal failure, and hepatic injury following chromic acid ingestion, and subsequently died. Postmortem liver and kidney biopsies revealed centrilobular necrosis and severe acute tubular necrosis, respectively.

UI MeSH Term Description Entries
D007668 Kidney Body organ that filters blood for the secretion of URINE and that regulates ion concentrations. Kidneys
D008099 Liver A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances. Livers
D008297 Male Males
D009336 Necrosis The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
D011041 Poisoning A condition or physical state produced by the ingestion, injection, inhalation of or exposure to a deleterious agent. Poisonings
D002840 Chromates Salts of chromic acid containing the CrO(2-)4 radical. Chromate
D006471 Gastrointestinal Hemorrhage Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM. Hematochezia,Hemorrhage, Gastrointestinal,Gastrointestinal Hemorrhages,Hematochezias
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D001706 Biopsy Removal and pathologic examination of specimens from the living body. Biopsies

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