BIOMAT Database Logo BIOMAT Database Logo

Regulation of adenylate cyclase coupled beta-adrenergic receptors. 1976

R J Lefkowitz, and C Mukherjee, and L E Limbird, and M G Caron, and L T Williams, and R W Alexander, and J V Mickey, and R Tate

UI MeSH Term Description Entries
D007545 Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant. Isoprenaline,Isopropylarterenol,4-(1-Hydroxy-2-((1-methylethyl)amino)ethyl)-1,2-benzenediol,Euspiran,Isadrin,Isadrine,Isopropyl Noradrenaline,Isopropylnoradrenaline,Isopropylnorepinephrine,Isoproterenol Hydrochloride,Isoproterenol Sulfate,Isuprel,Izadrin,Norisodrine,Novodrin,Hydrochloride, Isoproterenol,Noradrenaline, Isopropyl,Sulfate, Isoproterenol
D007700 Kinetics The rate dynamics in chemical or physical systems.
D009638 Norepinephrine Precursor of epinephrine that is secreted by the ADRENAL MEDULLA and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers, and of the diffuse projection system in the brain that arises from the LOCUS CERULEUS. It is also found in plants and is used pharmacologically as a sympathomimetic. Levarterenol,Levonorepinephrine,Noradrenaline,Arterenol,Levonor,Levophed,Levophed Bitartrate,Noradrenaline Bitartrate,Noradrénaline tartrate renaudin,Norepinephrin d-Tartrate (1:1),Norepinephrine Bitartrate,Norepinephrine Hydrochloride,Norepinephrine Hydrochloride, (+)-Isomer,Norepinephrine Hydrochloride, (+,-)-Isomer,Norepinephrine d-Tartrate (1:1),Norepinephrine l-Tartrate (1:1),Norepinephrine l-Tartrate (1:1), (+,-)-Isomer,Norepinephrine l-Tartrate (1:1), Monohydrate,Norepinephrine l-Tartrate (1:1), Monohydrate, (+)-Isomer,Norepinephrine l-Tartrate (1:2),Norepinephrine l-Tartrate, (+)-Isomer,Norepinephrine, (+)-Isomer,Norepinephrine, (+,-)-Isomer
D011433 Propranolol A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs. Dexpropranolol,AY-20694,Anaprilin,Anapriline,Avlocardyl,Betadren,Dociton,Inderal,Obsidan,Obzidan,Propanolol,Propranolol Hydrochloride,Rexigen,AY 20694,AY20694,Hydrochloride, Propranolol
D011941 Receptors, Adrenergic Cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger intracellular changes. The two major classes of adrenergic receptors, alpha and beta, were originally discriminated based on their cellular actions but now are distinguished by their relative affinity for characteristic synthetic ligands. Adrenergic receptors may also be classified according to the subtypes of G-proteins with which they bind; this scheme does not respect the alpha-beta distinction. Adrenergic Receptors,Adrenoceptor,Adrenoceptors,Norepinephrine Receptor,Receptors, Epinephrine,Receptors, Norepinephrine,Adrenergic Receptor,Epinephrine Receptors,Norepinephrine Receptors,Receptor, Adrenergic,Receptor, Norepinephrine
D001798 Blood Proteins Proteins that are present in blood serum, including SERUM ALBUMIN; BLOOD COAGULATION FACTORS; and many other types of proteins. Blood Protein,Plasma Protein,Plasma Proteins,Serum Protein,Serum Proteins,Protein, Blood,Protein, Plasma,Protein, Serum,Proteins, Blood,Proteins, Plasma,Proteins, Serum
D002462 Cell Membrane The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells. Plasma Membrane,Cytoplasmic Membrane,Cell Membranes,Cytoplasmic Membranes,Membrane, Cell,Membrane, Cytoplasmic,Membrane, Plasma,Membranes, Cell,Membranes, Cytoplasmic,Membranes, Plasma,Plasma Membranes
D004789 Enzyme Activation Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme. Activation, Enzyme,Activations, Enzyme,Enzyme Activations
D004837 Epinephrine The active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS. Adrenaline,4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol,Adrenaline Acid Tartrate,Adrenaline Bitartrate,Adrenaline Hydrochloride,Epifrin,Epinephrine Acetate,Epinephrine Bitartrate,Epinephrine Hydrochloride,Epinephrine Hydrogen Tartrate,Epitrate,Lyophrin,Medihaler-Epi,Acetate, Epinephrine
D004912 Erythrocytes Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN. Blood Cells, Red,Blood Corpuscles, Red,Red Blood Cells,Red Blood Corpuscles,Blood Cell, Red,Blood Corpuscle, Red,Erythrocyte,Red Blood Cell,Red Blood Corpuscle

Related Publications

R J Lefkowitz, and C Mukherjee, and L E Limbird, and M G Caron, and L T Williams, and R W Alexander, and J V Mickey, and R Tate
Heterogeneity of adenylate cyclase-coupled beta-adrenergic receptors.
March 1975, Biochemical pharmacology,
R J Lefkowitz, and C Mukherjee, and L E Limbird, and M G Caron, and L T Williams, and R W Alexander, and J V Mickey, and R Tate
Identification of adenylate cyclase-coupled beta-adrenergic receptors with radiolabeled beta-adrenergic antagonists.
September 1975, Biochemical pharmacology,
R J Lefkowitz, and C Mukherjee, and L E Limbird, and M G Caron, and L T Williams, and R W Alexander, and J V Mickey, and R Tate
Adenylate cyclase coupled beta-adrenergic receptors: biochemical mechanisms of desensitization.
January 1986, Clinical neuropharmacology,
R J Lefkowitz, and C Mukherjee, and L E Limbird, and M G Caron, and L T Williams, and R W Alexander, and J V Mickey, and R Tate
Adenylate cyclase coupled beta adrenergic receptors of Rauscher erythroleukemia cells.
August 1981, Biochemical and biophysical research communications,
R J Lefkowitz, and C Mukherjee, and L E Limbird, and M G Caron, and L T Williams, and R W Alexander, and J V Mickey, and R Tate
Regulation of adenylyl cyclase-coupled beta-adrenergic receptors.
January 1988, Annual review of cell biology,
R J Lefkowitz, and C Mukherjee, and L E Limbird, and M G Caron, and L T Williams, and R W Alexander, and J V Mickey, and R Tate
Beta-adrenergic receptor-coupled adenylate cyclase. Biochemical mechanisms of regulation.
January 1987, Molecular neurobiology,
R J Lefkowitz, and C Mukherjee, and L E Limbird, and M G Caron, and L T Williams, and R W Alexander, and J V Mickey, and R Tate
Molecular pharmacology of adenylate cyclase-coupled alpha- and beta-adrenergic receptors.
January 1981, Advances in cyclic nucleotide research,
R J Lefkowitz, and C Mukherjee, and L E Limbird, and M G Caron, and L T Williams, and R W Alexander, and J V Mickey, and R Tate
Ectopic beta-adrenergic receptors coupled to adenylate cyclase in human adrenocortical carcinomas.
May 1985, The Journal of clinical endocrinology and metabolism,
R J Lefkowitz, and C Mukherjee, and L E Limbird, and M G Caron, and L T Williams, and R W Alexander, and J V Mickey, and R Tate
Regulation of adenylate cyclase-coupled beta adrenergic receptor binding sites by beta adrenergic catecholamines in vitro.
May 1976, Molecular pharmacology,
R J Lefkowitz, and C Mukherjee, and L E Limbird, and M G Caron, and L T Williams, and R W Alexander, and J V Mickey, and R Tate
Molecular mechanisms of activation and desensitization of adenylate cyclase coupled beta-adrenergic receptors.
January 1978, Advances in cyclic nucleotide research,
Copied contents to your clipboard!