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There is growing evidence that AD consists of different subtypes, and that language is a pertinent factor to identify a subgroup with a fast rate of cognitive decline. We report the first results of a longitudinal study in which we compared two groups of patients with probable AD. The main result showed that a subgroup with stable MMSE scores during a 1-year follow-up period had an impairment in language domains which are usually preserved until an advanced stage of the disease. It is proposed that this group may correspond to a variety of AD who, in addition to symptoms of AD, present characteristics of primary progressive aphasia. In other respects, we underscore that the high loading in language-mediated tasks of the MMSE makes it a poor index to accurately measure the rate of cognitive decline.
M C Goldblum, and
C Tzortzis, and
J L Michot, and
M Panisset, and
F Boller
January 2021,
Current Alzheimer research,
M C Goldblum, and
C Tzortzis, and
J L Michot, and
M Panisset, and
F Boller
November 2003,
Neurology,
M C Goldblum, and
C Tzortzis, and
J L Michot, and
M Panisset, and
F Boller
January 2009,
Journal of Alzheimer's disease : JAD,
M C Goldblum, and
C Tzortzis, and
J L Michot, and
M Panisset, and
F Boller
July 1996,
Brain and cognition,
M C Goldblum, and
C Tzortzis, and
J L Michot, and
M Panisset, and
F Boller
February 2001,
Neurology,
M C Goldblum, and
C Tzortzis, and
J L Michot, and
M Panisset, and
F Boller
November 2021,
Journal of speech, language, and hearing research : JSLHR,
M C Goldblum, and
C Tzortzis, and
J L Michot, and
M Panisset, and
F Boller
May 2020,
Aging & mental health,
M C Goldblum, and
C Tzortzis, and
J L Michot, and
M Panisset, and
F Boller
March 2007,
Neurology,
M C Goldblum, and
C Tzortzis, and
J L Michot, and
M Panisset, and
F Boller
August 2006,
Neurology,
M C Goldblum, and
C Tzortzis, and
J L Michot, and
M Panisset, and
F Boller
February 2000,
Annals of medicine,
