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The mathematical model of the physiological estrous cycle of the laboratory rat was developed. The data on physiological concentration of the hormones, participating in the estrous cycle regulation and admittances on the growth and selection of the ovarian follicles made the base of the model. The developed system of differentiated equations allowed to reproduce quiet precisely the duration of the estrous cycle phases, to follow up the behaviour of the apparent cohort of the growing ovarian follicles during several cycles. The model is a base for the studying of the effect of the different factors on the estrous cycle.
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