BIOMAT Database Logo BIOMAT Database Logo

Cytokines regulate proliferation and cytoskeletal organization of vascular smooth muscle cells. 1994

G K Hansson
Gothenburg University, Department of Clinical Chemistry, Sahlgren's Hospital, Sweden.

The vasculature is an important target for inflammatory reactions, which may evolve into subsequent fibrosis. In large vessels, fibrotic lesions develop after invasive manipulations such as angioplasty. This results in stenotic arteries and represents a major clinical problem in cardiology. Local production of cytokines and growth factors both by vascular endothelial and smooth muscle cells and by blood-borne, immunocompetent cells are important regulators of these events. The present review summarizes experimental studies on the role of immune-derived cytokines in vascular cell biology and pathology.

UI MeSH Term Description Entries
D009131 Muscle, Smooth, Vascular The nonstriated involuntary muscle tissue of blood vessels. Vascular Smooth Muscle,Muscle, Vascular Smooth,Muscles, Vascular Smooth,Smooth Muscle, Vascular,Smooth Muscles, Vascular,Vascular Smooth Muscles
D002455 Cell Division The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION. M Phase,Cell Division Phase,Cell Divisions,Division Phase, Cell,Division, Cell,Divisions, Cell,M Phases,Phase, Cell Division,Phase, M,Phases, M
D003599 Cytoskeleton The network of filaments, tubules, and interconnecting filamentous bridges which give shape, structure, and organization to the cytoplasm. Cytoplasmic Filaments,Cytoskeletal Filaments,Microtrabecular Lattice,Cytoplasmic Filament,Cytoskeletal Filament,Cytoskeletons,Filament, Cytoplasmic,Filament, Cytoskeletal,Filaments, Cytoplasmic,Filaments, Cytoskeletal,Lattice, Microtrabecular,Lattices, Microtrabecular,Microtrabecular Lattices
D005109 Extracellular Matrix A meshwork-like substance found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere. Matrix, Extracellular,Extracellular Matrices,Matrices, Extracellular
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D016207 Cytokines Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner. Cytokine

Related Publications

G K Hansson
Proinflammatory cytokines regulate LOX-1 expression in vascular smooth muscle cells.
October 2004, Arteriosclerosis, thrombosis, and vascular biology,
G K Hansson
Phospholipase C Isoforms, Cytoskeletal Organization, and Vascular Smooth Muscle Differentiation.
February 2000, News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society,
G K Hansson
Prostanoids regulate proliferation of vascular smooth muscle cells induced by arginine vasopressin.
February 2000, European journal of pharmacology,
G K Hansson
Cytokines and growth factors involved in apoptosis and proliferation of vascular smooth muscle cells.
September 2005, International immunopharmacology,
G K Hansson
Multiple cytokines regulate the expression of extracellular superoxide dismutase in human vascular smooth muscle cells.
August 2000, Atherosclerosis,
G K Hansson
Thrombin and proliferation of vascular smooth muscle cells.
October 1995, Circulation research,
G K Hansson
Adenylyl cyclase isoform-selective regulation of vascular smooth muscle proliferation and cytoskeletal reorganization.
October 2006, Circulation research,
G K Hansson
Ligustilide inhibits vascular smooth muscle cells proliferation.
August 2006, European journal of pharmacology,
G K Hansson
Potassium channels and proliferation of vascular smooth muscle cells.
December 2005, Circulation research,
G K Hansson
LncRNA UCA1 sponges miR-26a to regulate the migration and proliferation of vascular smooth muscle cells.
October 2018, Gene,
Copied contents to your clipboard!