-transparent.png){kind=logo}
A GC-MSD method for the determination of tetramethylpyrazine (TMP) and borneol in plasma is described. TMP and borneol were extracted with hexane-dichloromethane (10:1, V/V). Camphor was used as the internal standard. The average recoveries of TMP and borneol were 87.38% and 97.32% with relative standard deviation 1.90% to 6.21%, respectively. The method was successfully used to determine plasma borneol concentration following sublingual administration of 20 pills of Suxiao Jiuxin Wan to healthy volunteers (n = 10). The pharmacokinetic parameters have been listed in this paper.
Related Publications
L L Yang, and
Y S Yuan, and
Y L Tong, and
C Y Guo
January 1993,
Yao xue xue bao = Acta pharmaceutica Sinica,
L L Yang, and
Y S Yuan, and
Y L Tong, and
C Y Guo
July 1989,
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,
L L Yang, and
Y S Yuan, and
Y L Tong, and
C Y Guo
January 1990,
Zhongguo yao li xue bao = Acta pharmacologica Sinica,
L L Yang, and
Y S Yuan, and
Y L Tong, and
C Y Guo
December 2005,
Analytical biochemistry,
L L Yang, and
Y S Yuan, and
Y L Tong, and
C Y Guo
April 2014,
Journal of separation science,
L L Yang, and
Y S Yuan, and
Y L Tong, and
C Y Guo
October 2014,
Journal of pharmaceutical analysis,
L L Yang, and
Y S Yuan, and
Y L Tong, and
C Y Guo
April 2009,
Journal of chromatographic science,
L L Yang, and
Y S Yuan, and
Y L Tong, and
C Y Guo
January 2004,
Journal of chromatographic science,
L L Yang, and
Y S Yuan, and
Y L Tong, and
C Y Guo
January 1992,
Yao xue xue bao = Acta pharmaceutica Sinica,
L L Yang, and
Y S Yuan, and
Y L Tong, and
C Y Guo
July 2009,
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,
