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In 1990-1992 110 patients with polycystic kidney disease adult type (ADPKD) were contacted. Forty-nine families were examined by Southern's RFLP method (standard probe 3'HVR and Pvu II restrictase). Of 424 members of these families only 25 (5.9%) refused the examination. So far 337 examinations were completed, 62 are under way. In 32 cases of 109 subjects at risk of 50% ADPKD the affection was proved with a probability higher than 95%, in 77 subjects (and 6 subjects with a 25% risk) were eliminated with an equal probability. In two families successful prenatal examinations of the foetus were accomplished. Evaluation of attitudes to DNA diagnostics revealed in our patients a greater willingness to attend postnatal examinations (up to 98%) and a smaller willingness to have prenatal examinations (21%), as compared with data published abroad.
J Kapras, and
J Stekrovä, and
J Zidovská, and
A Horínek, and
I Mazura, and
M Merta, and
R Brdicka
August 1995,
Casopis lekaru ceskych,
J Kapras, and
J Stekrovä, and
J Zidovská, and
A Horínek, and
I Mazura, and
M Merta, and
R Brdicka
July 2008,
Expert opinion on medical diagnostics,
J Kapras, and
J Stekrovä, and
J Zidovská, and
A Horínek, and
I Mazura, and
M Merta, and
R Brdicka
July 1986,
Lancet (London, England),
J Kapras, and
J Stekrovä, and
J Zidovská, and
A Horínek, and
I Mazura, and
M Merta, and
R Brdicka
September 1987,
Ugeskrift for laeger,
J Kapras, and
J Stekrovä, and
J Zidovská, and
A Horínek, and
I Mazura, and
M Merta, and
R Brdicka
January 1997,
Folia biologica,
J Kapras, and
J Stekrovä, and
J Zidovská, and
A Horínek, and
I Mazura, and
M Merta, and
R Brdicka
October 1994,
Archives of pediatrics & adolescent medicine,
J Kapras, and
J Stekrovä, and
J Zidovská, and
A Horínek, and
I Mazura, and
M Merta, and
R Brdicka
January 2011,
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia,
J Kapras, and
J Stekrovä, and
J Zidovská, and
A Horínek, and
I Mazura, and
M Merta, and
R Brdicka
October 2017,
Expert review of molecular diagnostics,
J Kapras, and
J Stekrovä, and
J Zidovská, and
A Horínek, and
I Mazura, and
M Merta, and
R Brdicka
January 2016,
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia,
J Kapras, and
J Stekrovä, and
J Zidovská, and
A Horínek, and
I Mazura, and
M Merta, and
R Brdicka
January 1992,
Folia medica,
