Biomaterial Database

Chronic renal dysfunction in hemorrhagic fever with renal syndrome patients. 1993

M Elisaf, and H Korakis, and K C Siamopoulos

Department of Internal Medicine, Medical School, University of Ioannina, Greece.

During the last 9 years, 32 cases of hemorrhagic fever with renal syndrome (HFRS) have been diagnosed in our institution. Seven patients died. Twenty-three patients were discharged healthy while in another 2 some degree of renal dysfunction, which remained stable 12-15 months later, was evident. In 12 out of the 23 healthy individuals thorough examination of renal function was performed 1-5 years after their discharge. Three out of the 12 had renal tubular acidosis (RTA) type I (distal), complete or incomplete, and 2 (1 of whom also had incomplete RTA) had reduced urine concentrating ability. The development of chronic renal dysfunction was independent of the clinical severity of the acute illness.

UI	MeSH Term	Description	Entries
D007671	Kidney Concentrating Ability	The ability of the kidney to excrete in the urine high concentrations of solutes from the blood plasma.	Urine Concentrating Ability,Abilities, Kidney Concentrating,Abilities, Urine Concentrating,Ability, Kidney Concentrating,Ability, Urine Concentrating,Concentrating Abilities, Kidney,Concentrating Abilities, Urine,Concentrating Ability, Kidney,Concentrating Ability, Urine,Kidney Concentrating Abilities,Urine Concentrating Abilities
D007676	Kidney Failure, Chronic	The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.	ESRD,End-Stage Renal Disease,Renal Disease, End-Stage,Renal Failure, Chronic,Renal Failure, End-Stage,Chronic Kidney Failure,End-Stage Kidney Disease,Chronic Renal Failure,Disease, End-Stage Kidney,Disease, End-Stage Renal,End Stage Kidney Disease,End Stage Renal Disease,End-Stage Renal Failure,Kidney Disease, End-Stage,Renal Disease, End Stage,Renal Failure, End Stage
D007677	Kidney Function Tests	Laboratory tests used to evaluate how well the kidneys are working through examination of blood and urine.	Function Test, Kidney,Function Tests, Kidney,Kidney Function Test,Test, Kidney Function,Tests, Kidney Function
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D005260	Female		Females
D005500	Follow-Up Studies	Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.	Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006115	Greece	A country in southern Europe, bordering the Aegean Sea, Ionian Sea, and the Mediterranean Sea, between Albania and Turkey. The capital is Athens.	Crete,Macedonia (Greece)
D006480	Hemorrhagic Fever with Renal Syndrome	An acute febrile disease occurring predominately in Asia. It is characterized by fever, prostration, vomiting, hemorrhagic phenonema, shock, and renal failure. It is caused by any one of several closely related species of the genus ORTHOHANTAVIRUS. The most severe form is caused by HANTAAN VIRUS whose natural host is the rodent Apodemus agrarius. Milder forms are caused by SEOUL VIRUS and transmitted by the rodents Rattus rattus and R. norvegicus, and the PUUMALA VIRUS with transmission by Clethrionomys galreolus.	HFRS,Hemorrhagic Fever, Epidemic,Hemorrhagic Fever, Korean,Hemorrhagic Nephroso-Nephritis,Nephropathia Epidemica,Epidemic Hemorrhagic Fever,Epidemic Hemorrhagic Fevers,Hemorrhagic Fevers, Epidemic,Hemorrhagic Nephroso Nephritis,Hemorrhagic Nephroso-Nephritides,Korean Hemorrhagic Fever,Nephroso-Nephritides, Hemorrhagic,Nephroso-Nephritis, Hemorrhagic
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man